1-Methyl-3-((thiophen-2-ylmethyl)amino)-1H-pyrazole-5-carboxamide hydrochloride CAS 1856085-52-3
| CAS No. | 1856085-52-3 |
| Molecular Formula | C10H12N4OS |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Methyl-3-((thiophen-2-ylmethyl)amino)-1H-pyrazole-5-carboxamide hydrochloride (CAS 1856085-52-3), molecular formula C10H12N4OSHCl and molecular weight 272.75 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Methyl-3-((thiophen-2-ylmethyl)amino)-1H-pyrazole-5-carboxamide hydrochloride (C10H12N4OSHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12N4OS HCl |
| Molecular Weight | 272.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 4-(Thiophen-2-ylmethyl)benzonitrile (CAS 100005-79-6)
- 1-(Thiophen-2-yl)cyclohexane-1-carboxylic acid (CAS 100058-72-8)
- 1-Methyl-4-(thiophen-2-yl)piperidin-4-ol (CAS 100131-91-7)
- 1-(Thiophen-2-yl)cyclohexan-1-amine (CAS 100133-00-4)
- Ethyl 2-((5-(3-(thiophen-2-yl)ureido)-1,3,4-thiadiazol-2-yl)thio)acetate (CAS 1001830-00-7)
- 2-((5-(3-(Thiophen-2-yl)ureido)-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 1002043-11-9)
- 4-(Thiophen-2-ylmethyl)benzoic acid (CAS 1002727-90-3)
- Methyl(thiophen-2-yl)cyanocarbonimidodithioate (CAS 100477-76-7)
Recommended Standards
- Bis(pyridin-3-ylmethyl)amine (CAS 1656-94-6)
- ethyl 4-[(aminocarbonothioyl)amino]piperidine-1-carboxylate (CAS 294622-57-4)
- n,1-Dimethylazetidin-3-amine dihydrochloride (CAS 864247-47-2)
- (S)-2,3-Dihydrobenzofuran-3-amine hydrochloride (CAS 1459793-02-2)
- (3R,4R)-1-Boc-pyrrolidine-3,4-dicarboxylic Acid (CAS 1807916-65-9)
- 1,1,1,2,2-Pentafluoro-3-iodopropane (CAS 354-69-8)
- 3-Bromo-7-methoxy-5,6,7,8-tetrahydropyrazolo[5,1-b][1,3]oxazepine (CAS 2409128-06-7)
- 9-((2-Hydroxy-3-methylbut-3-en-1-yl)oxy)-7H-furo[3,2-g]chromen-7-one (CAS 53319-52-1)
- Lincomycin Sulfoxide (Mixture of Diastereomers) (CAS 22083-92-7)
- Semaglutide Impurity 143 (CAS CATO-C4X-2226143)
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