2-Chloro-N-cyclohexyl-N-(2,5-dioxo-1-phenylpyrrolidin-3-yl)acetamide CAS 1858240-89-7
| CAS No. | 1858240-89-7 |
| Molecular Formula | C18H21ClN2O3 |
| Molecular Weight | 348.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Chloro-N-cyclohexyl-N-(2,5-dioxo-1-phenylpyrrolidin-3-yl)acetamide (CAS 1858240-89-7), molecular formula C18H21ClN2O3 and molecular weight 348.82 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Chloro-N-cyclohexyl-N-(2,5-dioxo-1-phenylpyrrolidin-3-yl)acetamide (C18H21ClN2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H21ClN2O3 |
| Molecular Weight | 348.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- Ethyl 3-chloro-5-ethoxy-4-((2-methylbenzyl)oxy)benzoate (CAS 1706457-95-5)
- (1-(3-Chloro-4-fluorophenyl)-3-(4-(methylthio)phenyl)-1H-pyrazol-4-yl)methanol (CAS 618444-53-4)
- 5-(5-(2-Chloro-4-(4,5-dihydrooxazol-2-yl)phenoxy)pentyl)-3-methyl-2,3-dihydrooxazole (CAS 98033-68-2)
- Ethyl 1-((5-chloro-8-hydroxyquinolin-7-yl)methyl)piperidine-4-carboxylate (CAS 325992-62-9)
- (2Z)-3-[(4-Chloro-6-methylpyrimidin-2-yl)amino]-2-(4-methylbenzenesulfonyl)prop-2-enenitrile (CAS 1025678-47-0)
- 1-(3-Chloro-2-methylphenyl)-3-(1-(3-methyl-1,2,4-oxadiazol-5-yl)cyclohexyl)urea (CAS 1396765-53-9)
- 2-(5-((2-Chloro-6-fluorobenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)pyridine (CAS 577787-21-4)
- 2-[(5-Chloro-1,3-dimethyl-1H-pyrazol-4-yl)formamido]-N-[4-(propan-2-yl)phenyl]acetamide (CAS 955976-68-8)
Recommended Standards
- Bisphenol F Glycidyl (2-Chloro-1-propanol) Ether (CAS 194672-61-2)
- N-(2-chloro-6-(1H-1,2,4-triazol-1-yl)benzyl)benzenesulfonamide (CAS 866042-60-6)
- Ethyl 2-(6-((4-chlorophenyl)thio)-9H-purin-9-yl)acetate (CAS 646509-72-0)
- (2E)-3-[4-(Benzyloxy)phenyl]-1-(2-chlorophenyl)prop-2-en-1-one (CAS 909774-57-8)
- 4-(5-Bromopyridin-2-yl)butanoic acid (CAS 1454928-83-6)
- 1-Pentyl-1h-1,2,4-triazol-3-amine (CAS 1182952-47-1)
- (2R,3R)-(-)-2,3-Bis(diphenylphosphino)bicyclo[2.2.1]hept-5-ene (CAS 76740-45-9)
- 5-Amino-6-fluoro-8-methylquinoline-2-carboxylic acid (CAS 1420792-51-3)
- (E)-1-(2-Hydroxy-3,4,6-trimethoxyphenyl)-3-phenylprop-2-en-1-one (CAS 91856-16-5)
- 3-(2-Bromo-1-hydroxyethyl)-5-chlorothiophene-2-sulfonamide (CAS 174139-67-4)
- 2-Phenyl-5,6,7,8-tetrahydroquinazolin-6-amine dihydrochloride (CAS 1193389-46-6)
- Dapagliflozin Propanediol Hydrate (CAS 960404-48-2)
- 1-(4-Methoxyphenyl)-1,2-diphenylbutan- 1-ol (CAS 650624-50-3)
- Tirzepatide Impurity 14 (CAS CATO-C4X-324014)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com