2-(2-chlorophenyl)quinazoline-4-thiol CAS 18590-76-6
| CAS No. | 18590-76-6 |
| Molecular Formula | C14H25ClN2S |
| Molecular Weight | 288.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-chlorophenyl)quinazoline-4-thiol.
CATO supplies 2-(2-chlorophenyl)quinazoline-4-thiol (CAS 18590-76-6), a certified reference material (molecular formula C14H25ClN2S, MW 288.88 g/mol) for analytical method development and quality control.
2-(2-chlorophenyl)quinazoline-4-thiol (C14H25ClN2S) contains a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(2-chlorophenyl)quinazoline-4-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H25ClN2S |
| Molecular Weight | 288.88 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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- 2-(4-Chlorophenyl)-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole (CAS 63208-73-1)
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- 1-(6-(2-Chlorophenyl)pyridazin-3-yl)piperidin-3-amine (CAS 1338657-88-7)
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Recommended Standards
- tert-Butyl[2-(4-chloro-2-fluorophenyl)ethoxy]dimethylsilane (CAS 1881296-44-1)
- 3,5-Dichloro-2-iodophenol (CAS 1028332-19-5)
- 2-Bromoiodobenzene-<SUP>13</SUP>C<SUB>6</SUB> (CAS 1173023-32-9)
- 4,6-Dichloro-5-iodo-2-methylpyrimidine (CAS 111079-21-1)
- 4-Fluoropiperidine-4-carboxylic acid (CAS 1187087-08-6)
- 4-Bromo-N-(4-(2,5-dimethyl-1H-pyrrol-1-yl)phenyl)benzenesulfonamide (CAS 866156-51-6)
- m-Xylenes（xylene isomer and ethyl benzene） (CAS 1330-20-7)
- N1-(2-chloroethanimidoyl)-3-chloro-4-fluorobenzene-1-sulphonamide (CAS 219619-70-2)
- 1-(3-Methoxy-4-nitrophenyl)pyrrolidin-3-ol (CAS 761440-58-8)
- 3-Methoxy-1-methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid (CAS 1379202-82-0)
- 4-Amino-6-(difluoromethyl)-5-fluoropicolinaldehyde (CAS 1805111-33-4)
- 3-Chloro-5-(pyrrolidin-1-ylsulfonyl)pyridin-4(1H)-one (CAS 1352515-67-3)
- 3-Methyl-4-(3-(trifluoromethyl)benzoyl)-3,4-dihydroquinoxalin-2(1H)-one (CAS 317822-26-7)
- Semaglutide impurity 197 (CAS CATO-C4X-2226197)
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