2-thien-2-ylquinazoline-4-thiol CAS 18590-68-6

Purity 97%+In StockPharmaceutical Standards
CAS No.18590-68-6
Molecular FormulaC12H8N2S2
Molecular Weight244.34 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-thien-2-ylquinazoline-4-thiol CAS 18590-68-6 chemical structure

Description

2-thien-2-ylquinazoline-4-thiol (CAS 18590-68-6), molecular formula C12H8N2S2 and molecular weight 244.34 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-thien-2-ylquinazoline-4-thiol (C12H8N2S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-thien-2-ylquinazoline-4-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H8N2S2
Molecular Weight244.34 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1962
Nitrogen Atoms2
Sulfur Atoms2

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