Phloroglucinol Impurity 78 CAS 18612-99-2

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.18612-99-2
Molecular FormulaC10H12O
Molecular Weight148.20 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Phloroglucinol Impurity 78 CAS 18612-99-2 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

CATO supplies Phloroglucinol Impurity 78 (CAS 18612-99-2), a pharmacopoeial impurity reference standard (molecular formula C10H12O, MW 148.20 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Phloroglucinol Impurity 78 (C10H12O) is characterized by a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

Physical & Chemical Properties

Molecular FormulaC10H12O
Molecular Weight148.20 g/mol
Purity>90%
StorageStore at 2-8°C
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityStable under recommended storage conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1962

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