4-Chloro-8-fluoro-2-methylquinoline CAS 18615-59-3
| CAS No. | 18615-59-3 |
| Molecular Formula | C10H17ClFN |
| Molecular Weight | 205.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 205.70 g/mol gives 4-Chloro-8-fluoro-2-methylquinoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-Chloro-8-fluoro-2-methylquinoline (CAS 18615-59-3), a certified reference material (molecular formula C10H17ClFN, MW 205.70 g/mol) for analytical method development and quality control.
Based on its molecular formula C10H17ClFN, 4-Chloro-8-fluoro-2-methylquinoline contains a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic molecular-ion distribution patterns in mass spectrometry. The molecular weight of 205.70 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H17ClFN |
| Molecular Weight | 205.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- (2R)-2-(3-chloro-4-fluorophenyl)pyrrolidine (CAS 1241678-96-5)
- 2-Chloro-7-fluoro-3-methylquinoline (CAS 132118-48-0)
- 6-chloro-7-fluoro-2-methyl-quinoline (CAS 1491163-25-7)
- 4-Chloro-7-fluoro-2-methylquinoline (CAS 18529-04-9)
- 2-chloro-1,3-benzothiazin-4-one (CAS 7742-71-4)
- 4-chloro-6-fluoro-7-methyl-quinoline (CAS 2216746-75-5)
- 4-chloro-7-methoxypyrido[3,2-d]pyrimidine (CAS 1256811-43-4)
- 4-chloro-8-methoxy-pyrido[3,4-d]pyrimidine (CAS 1260178-67-3)
Recommended Standards
- 4-(Chloromethyl)-2-(2-methoxypropan-2-yl)thiazole (CAS 1503142-43-5)
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- 7-chlorothieno[3,2-b]pyridine-2-carbaldehyde (CAS 387819-41-2)
- 3-Amino-1-(5-chlorothiophen-2-yl)-2-methylpropan-1-ol (CAS 1502057-52-4)
- 4-Bromo-5,6-dihydro-pyrrolo[3,4-b]pyridin-7-one (CAS 1823870-64-9)
- 1-bromo-4-(chloromethyl)-2,5-dimethoxybenzene (CAS 446831-24-9)
- 3-chloro-1,1,2-trifluorocyclobutane (CAS 38310-68-8)
- (S)-4-Methyl-2,3-dihydro-1H-inden-1-amine hydrochloride (CAS 2109874-04-4)
- 5-Amino-2-(pyrazin-2-yl)oxazole-4-carbonitrile (CAS 907962-52-1)
- 4'-(Piperidine-1-carbonyl)-[1,1'-biphenyl]-4-carbonitrile (CAS 1365271-75-5)
- Benzo[b]thiophene-4-carboxamide (CAS 17347-35-2)
- 4-Chloro-1-cyclopentyl-1H-pyrazole-3-carboxylic acid (CAS 1006451-33-7)
- 6-Chloro-N5-methylpyrimidine-4,5-diamine (CAS 55286-10-7)
- Tau Peptide (275-305) (Repeat 2 Domain) trifluoroacetate salt (CAS 330456-25-2)
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