tert-Butyl (2,2,2-trifluoro-1-(pyrrolidin-3-yl)ethyl)carbamate CAS 186202-31-3
| CAS No. | 186202-31-3 |
| Molecular Formula | C11H19F3N2O2 |
| Molecular Weight | 268.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies tert-Butyl (2,2,2-trifluoro-1-(pyrrolidin-3-yl)ethyl)carbamate (CAS 186202-31-3), a certified reference material (molecular formula C11H19F3N2O2, MW 268.28 g/mol) for analytical method development and quality control.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, tert-Butyl (2,2,2-trifluoro-1-(pyrrolidin-3-yl)ethyl)carbamate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 268.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H19F3N2O2 |
| Molecular Weight | 268.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- (Dimethylphenylsilyl)pinacol borate (CAS 185990-03-8)
- Tert-butyl ((3-(trifluoromethyl)pyrrolidin-3-yl)methyl)carbamate (CAS 186203-22-5)
- tert-Butyl (2-(trifluoromethyl)piperidin-3-yl)carbamate (CAS 1824347-45-6)
- tert-butyl 2-(aminomethyl)-2-(trifluoromethyl)pyrrolidine-1-carboxylate (CAS 1893669-47-0)
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Why CATO?
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