tert-butyl 2-(aminomethyl)-2-(trifluoromethyl)pyrrolidine-1-carboxylate CAS 1893669-47-0
| CAS No. | 1893669-47-0 |
| Molecular Formula | C11H19F3N2O2 |
| Molecular Weight | 268.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of tert-butyl 2-(aminomethyl)-2-(trifluoromethyl)pyrrolidine-1-carboxylate (C11H19F3N2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies tert-butyl 2-(aminomethyl)-2-(trifluoromethyl)pyrrolidine-1-carboxylate (CAS 1893669-47-0), a certified reference material (molecular formula C11H19F3N2O2, MW 268.28 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H19F3N2O2 |
| Molecular Weight | 268.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Tert-butyl ((3-(trifluoromethyl)pyrrolidin-3-yl)methyl)carbamate (CAS 186203-22-5)
- (S)-4-(tert-Butoxy)-2-(4-fluorophenyl)-4-oxobutanoic acid (CAS 1923069-43-5)
- tert-Butyl (2,2,2-trifluoro-1-(pyrrolidin-3-yl)ethyl)carbamate (CAS 186202-31-3)
- Tert-butyl (2S,3R)-3-amino-2-(trifluoromethyl)piperidine-1-carboxylate (CAS 1931908-19-8)
- 3-Butoxy-4-methylbenzaldehyde (CAS 1379202-65-9)
- 1-AMINO-6-FLUORO-2,3-DIHYDRO-1H-INDENE-1-CARBOXYLIC ACID (CAS 1270433-43-6)
- N-(3-Morpholin-4-ylpropyl)-N-(4-nitrophenyl)amine (CAS 503629-24-1)
- 12(S)-Hydroxy (5Z,8Z,10E,14Z)-Eicosatetraenoic Acid (CAS 54397-83-0)
- 6-(Aminomethyl)-5-cyclopropoxy-N,N-dimethylpicolinamide (CAS 1243383-49-4)
- Ethyl 2-chloro-6-phenylnicotinate (CAS 31676-61-6)
- 2,4-Dichloro-5-ethyl-6-methylpyrimidine (CAS 861033-35-4)
- Methyl (S)-pyrrolidin-3-ylcarbamate (CAS 133298-84-7)
- Nicorandil Impurity 19 (CAS CATO-C4X-190719)
- Semaglutide-d8 Tetratrifluoroacetate (CAS CATO-C4X-222617)
Why CATO?
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