2-Amino-5-bromo-3-fluorophenol CAS 186309-73-9
| CAS No. | 186309-73-9 |
| Molecular Formula | C6H5BrFNO |
| Molecular Weight | 206.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Amino-5-bromo-3-fluorophenol (CAS 186309-73-9), molecular formula C6H5BrFNO and molecular weight 206.01 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, 2-Amino-5-bromo-3-fluorophenol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 206.01 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-Amino-5-bromo-3-fluorophenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5BrFNO |
| Molecular Weight | 206.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- 2-Amino-4-bromo-5-fluorophenol (CAS 1016234-89-1)
- 2-Amino-5-bromo-4-fluorophenol (CAS 1037364-36-5)
- 4-Amino-2-bromo-5-fluorophenol (CAS 111856-96-3)
- 6-Amino-2-bromo-3-fluorophenol (CAS 1257535-00-4)
- 3-Amino-4-bromo-2-fluorophenol (CAS 1443107-59-2)
- 5-Amino-3-bromo-2-fluorophenol (CAS 1779831-28-5)
- 3-Amino-2-bromo-4-fluorophenol (CAS 1779831-32-1)
- 4-Amino-2-bromo-6-fluorophenol (CAS 1783544-55-7)
Recommended Standards
- 2-Amino-4-bromo-6-fluorophenol (CAS 182499-89-4)
- (4-Methyl-2-oxo-1,2,3,4-tetrahydroquinoxalin-6-yl)boronic acid (CAS 305790-80-1)
- 2-Amino-3-bromo-6-fluorophenol (CAS 1807234-87-2)
- (5-Methoxy-1-methyl-1H-pyrrolo[3,2-b]pyridin-6-yl)boronic acid (CAS 956407-29-7)
- Ethyl 3,5-dimethyl-1-(5-nitropyridin-2-yl)-1H-pyrazole-4-carboxylate (CAS 346440-94-6)
- 4-Bromo-1H-pyrrolo[2,3-c]pyridine-3-sulfonyl chloride (CAS 2138263-29-1)
- (S)-N-Methylhydroxysuccinimide-d3 (CAS CATO-CCHM705487)
- 3-Bromo-2-thienylmagnesium bromide 0.25 M in Tetrahydrofuran (CAS 119277-44-0)
- Methyl 5-(methylsulfonyl)-1H-indole-2-carboxylate (CAS 205873-28-5)
- 2-(4-Chloro-1H-pyrazol-1-yl)acetamide (CAS 1006506-31-5)
- 2,2,2-trifluoroethyl N-(4,5-dimethyl-1,3-oxazol-2-yl)carbamate (CAS 1423024-90-1)
- (5-Chloro-2-isopropylpyrimidine-4-carbonyl)glycine (CAS 1456103-81-3)
- 2-Propenoic acid, 2-methyl-, octadecyl ester, polymer with 2-propenoic acid, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (CAS 167078-17-3)
- D-Gln24-Tirzepatide (CAS CATO-CPTD788910)
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