3-Bromo-6-chloro-2-methyl-5-nitropyridine CAS 186413-75-2
| CAS No. | 186413-75-2 |
| Molecular Formula | C6H4BrClN2O2 |
| Molecular Weight | 251.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-Bromo-6-chloro-2-methyl-5-nitropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-Bromo-6-chloro-2-methyl-5-nitropyridine (CAS 186413-75-2), molecular formula C6H4BrClN2O2 and molecular weight 251.47 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system, 3-Bromo-6-chloro-2-methyl-5-nitropyridine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 251.47 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H4BrClN2O2 |
| Molecular Weight | 251.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 4-Bromo-3-chloro-2-nitroaniline (CAS 1000573-99-8)
- Methyl 6-bromo-5-chloropyrazine-2-carboxylate (CAS 1017603-87-0)
- 3-Bromo-2-chloro-4-methyl-5-nitropyridine (CAS 1049706-73-1)
- 2-Bromo-5-chloro-4-methyl-3-nitropyridine (CAS 1086838-26-7)
- methyl 3-bromo-5-chloro-pyrazine-2-carboxylate (CAS 1211592-50-5)
- 2-Bromo-6-chloro-3-methyl-5-nitropyridine (CAS 1225348-48-0)
- Methyl 6-Bromo-3-chloropyrazine-2-carboxylate (CAS 1256921-67-1)
- 2-Bromo-5-(chloromethyl)-3-nitropyridine (CAS 1379359-69-9)
Recommended Standards
- Methyl 5-bromo-6-chloropyrazine-2-carboxylate (CAS 1823961-84-7)
- 2-Amino-5-bromo-6-chloronicotinic acid (CAS 1889107-68-9)
- 6-Bromo-3-chloro-2-nitroaniline (CAS 1823903-57-6)
- 3-Amino-6-bromo-2-chloroisonicotinic acid (CAS 1934490-90-0)
- 5-(Phenylmethyl)-3-[(tetrahydro-2-furanyl)methyl]-2-thioxo-4-imidazolidinone (CAS 1008698-17-6)
- 3-[2-(difluoromethoxy)phenyl]-3-oxopropanenitrile (CAS 1016690-71-3)
- 3-(5-Fluoro-2-methoxyphenyl)azetidin-3-ol (CAS 1388055-33-1)
- (S)-3-(4-(difluoromethoxy)phenyl)morpholine (CAS 1213398-45-8)
- 1-Phenyl-3-(piperidin-1-yl)propan-2-amine (CAS 29618-49-3)
- Ethyl 2-(2-(chloromethyl)-1H-benzo[d]imidazol-6-yl)acetate (CAS 2547858-24-0)
- 1-(azidomethyl)-2-(trifluoromethyl)benzene (CAS 823189-03-3)
- n-(1,2,3,4-Tetrahydroquinolin-3-yl)acetamide (CAS 945-80-2)
- 2-(4-Isopropoxybenzamido)-6-isopropyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide hydrochloride (CAS 1215574-40-5)
- Tirzepatide Impurity 34 (CAS CATO-C4X-324034)
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