| CAS No. | 1868833-66-2 |
| Molecular Formula | C8H5F3O2S |
| Molecular Weight | 222.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 222.18 g/mol gives (2E)-3-[2-(trifluoromethyl)thiophen-3-yl]prop-2-enoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(2E)-3-[2-(trifluoromethyl)thiophen-3-yl]prop-2-enoic acid (CAS 1868833-66-2), molecular formula C8H5F3O2S and molecular weight 222.18 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, (2E)-3-[2-(trifluoromethyl)thiophen-3-yl]prop-2-enoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 222.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (2E)-3-[2-(trifluoromethyl)thiophen-3-yl]prop-2-enoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
| Molecular Formula | C8H5F3O2S |
| Molecular Weight | 222.18 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |