(2E)-3-[5-(trifluoromethyl)thiophen-3-yl]prop-2-enoic acid CAS 2044946-97-4
| CAS No. | 2044946-97-4 |
| Molecular Formula | C8H5F3O2S |
| Molecular Weight | 222.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2E)-3-[5-(trifluoromethyl)thiophen-3-yl]prop-2-enoic acid is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(2E)-3-[5-(trifluoromethyl)thiophen-3-yl]prop-2-enoic acid (CAS 2044946-97-4), molecular formula C8H5F3O2S and molecular weight 222.18 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, (2E)-3-[5-(trifluoromethyl)thiophen-3-yl]prop-2-enoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 222.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (2E)-3-[5-(trifluoromethyl)thiophen-3-yl]prop-2-enoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5F3O2S |
| Molecular Weight | 222.18 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related E Standards
- (2E)-3-[2-(trifluoromethyl)thiophen-3-yl]prop-2-enoic acid (CAS 1868833-66-2)
- 2-((Trifluoromethyl)thio)benzoic acid (CAS 37526-67-3)
- 3-((Trifluoromethyl)thio)benzoic acid (CAS 946-65-6)
- (6-(Trifluoromethyl)imidazo[2,1-b]thiazol-5-yl)methanol (CAS 1823883-23-3)
- 3-((Trifluoromethyl)thio)picolinamide (CAS 2385968-98-7)
- 1-ethyl-5-(trifluoromethyl)-1h-pyraZole-3-carbohydrazide (CAS 1001519-13-6)
- 1-ethyl-3-(trifluoromethyl)-1h-pyraZole-5-carbohydrazide (CAS 1004643-69-9)
- 2-[3-(trifluoromethyl)-1h-pyrazol-1-yl]propanehydrazide (CAS 1006327-06-5)
Recommended Standards
- (E)-4-(Diethoxyphosphoryl)but-2-enoic acid (CAS 79563-56-7)
- 5-((4-Fluorophenyl)amino)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1710194-80-1)
- (R)-3-(1-Aminoethyl)-4-fluoro-5-(trifluoromethyl)aniline (CAS 2230840-61-4)
- 5-(3-Fluoro-phenylamino)-1h-[1,2,3]triazole-4-carboxylic acid (CAS 1708428-34-5)
- 4-(3,5-Bis(4-bromophenyl)-4,5-dihydro-1h-pyrazol-1-yl)-4-oxobutanoic acid (CAS 313967-96-3)
- 3-Fluoro-4,4-dimethyl-pentan-1-amine (CAS 1554342-14-1)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)heptanedioic acid (CAS 1350450-51-9)
- 2-Fluoro-5-methoxy-4-methylbenzoic acid (CAS 870221-15-1)
- Olprinone Impurity 23 (CAS CATO-C4X-204323)
- Methyl 2-phenylacrylate (CAS 1865-29-8)
- 2-Chloro-4-(difluoromethyl)-3-methylpyridine (CAS 1806787-50-7)
- Atipamezole Impurity 2 (CAS 104054-24-2)
- (3-Fluoro-4-methylphenyl)hydrazine hydrochloride (CAS 156941-64-9)
- Semaglutide impurity 211 (CAS CATO-C4X-2226211)
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