(4-Amino-7-fluorocinnolin-3-yl)(4-(pyridin-2-yl)piperazin-1-yl)methanone CAS 187231-58-9
| CAS No. | 187231-58-9 |
| Molecular Formula | C18H17FN6O |
| Molecular Weight | 352.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (4-Amino-7-fluorocinnolin-3-yl)(4-(pyridin-2-yl)piperazin-1-yl)methanone is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 352.37 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
(4-Amino-7-fluorocinnolin-3-yl)(4-(pyridin-2-yl)piperazin-1-yl)methanone (CAS 187231-58-9), molecular formula C18H17FN6O and molecular weight 352.37 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H17FN6O |
| Molecular Weight | 352.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
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Recommended Standards
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- 1-((4-Fluorophenyl)[4-(trifluoromethyl)phenyl]methyl)-1,4-diazepane (CAS 503807-36-1)
- Berberine Impurity 3 (CAS 2435-73-6)
- 2-Difluoromethoxy-6-fluoroisonicotinic acid (CAS 1803823-54-2)
- 8,9-Dihydro-2-methyl-9-(4-methylphenyl)-8-oxo-7H-purine-6-carboxamide (CAS 932497-74-0)
- 1-(2-Ethoxy-3-methylphenyl)-N-methylmethanamine (CAS 709649-55-8)
- 1-(2-Isopropyl-1-methyl-1H-imidazol-5-yl)ethanone (CAS 403793-45-3)
- 2-Hydroxy-4-(trifluoromethyl)nicotinic acid (CAS 685125-22-8)
- 6-Oxa-2-azaspiro[3.4]octane 2,2,2-trifluoroacetic acid (CAS 1820712-05-7)
- 2-(Benzylthio)propanehydrazide (CAS 1002865-38-4)
- 1-Cyclopropyl-3-(5-((3-methoxybenzyl)thio)-1,3,4-thiadiazol-2-yl)urea (CAS 1323316-37-5)
- {4-[(morpholine-4-sulfonyl)methyl]phenyl}methanamine (CAS 1040344-10-2)
- Peptide Impurity 41 (CAS CATO-CPTD788841)
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