6-(Trifluoromethyl)tetrahydro-2H-pyran-3-carboxylic acid CAS 1878261-64-3
| CAS No. | 1878261-64-3 |
| Molecular Formula | C7H9F3O3 |
| Molecular Weight | 198.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C7H9F3O3, 6-(Trifluoromethyl)tetrahydro-2H-pyran-3-carboxylic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 198.14 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
6-(Trifluoromethyl)tetrahydro-2H-pyran-3-carboxylic acid (CAS 1878261-64-3), molecular formula C7H9F3O3 and molecular weight 198.14 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H9F3O3 |
| Molecular Weight | 198.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
Related Trifluoromethyl Standards
- 5-(trifluoromethyl)pyridazine-3-carboxylic acid (CAS 1211535-95-3)
- 3-(Trifluoromethyl)-1,8-naphthyridine (CAS 1261365-77-8)
- 2-[4-(trifluoromethyl)-1H-pyrazol-1-yl]acetic acid (CAS 1341347-35-0)
- 2-(Trifluoromethyl)quinoxaline (CAS 148853-42-3)
- 4-(Trifluoromethyl)tetrahydro-2H-pyran-4-carboxylic acid (CAS 1524761-14-5)
- 5-(Trifluoromethyl)quinazoline (CAS 16499-47-1)
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- 7-(Trifluoromethyl)quinazoline (CAS 16499-49-3)
Recommended Standards
- methyl 4-(2,2,2-trifluoroethoxy)but-2-enoate (CAS 1864760-24-6)
- 5-Methyl-2-(trifluoromethyl)tetrahydrofuran-3-carboxylic acid (CAS 1934521-12-6)
- 2-(Trifluoromethyl)tetrahydro-2H-pyran-4-carboxylic acid (CAS 1864428-00-1)
- 2,6-Diamino-5-nitropyrimidine-4-carboxamide (CAS 19796-69-1)
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- 2-(Chloromethyl)-6-(difluoromethyl)-5-methylpyridine-3-carboxylic acid (CAS 1105976-65-5)
- 8-Bromoisoquinolin-7-ol (CAS 660398-06-1)
- (R)-tert-Butyl 3-aminopiperidine-1-carboxylate hydrochloride (CAS 1152113-32-0)
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