Methionine Impurity 9 CAS 1879009-96-7
| CAS No. | 1879009-96-7 |
| Molecular Formula | C12H22N2O4S2 |
| Molecular Weight | 322.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Methionine Impurity 9 (CAS 1879009-96-7) is a certified pharmaceutical impurity reference standard with the molecular formula C12H22N2O4S2 and a molecular weight of 322.44 g/mol.
The molecular framework of Methionine Impurity 9 (C12H22N2O4S2) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H22N2O4S2 |
| Molecular Weight | 322.44 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Methionine Standards
- Methionine Impurity 2 (CAS CATO-C4X-18272)
- Methionine EP Impurity D (CAS CATO-C4X-18274)
- Methionine EP Impurity D (CAS CATO-C4X-18276)
- Methionine EP Impurity E (CAS CATO-C4X-18277)
- L-Methionine-d3-N-FMOC (S-methyl-d3) (CAS 502692-58-2)
- Methionine Impurity 11 (CAS 33770-86-4)
- Methionine impurity 10 (CAS CATO-C4X-182710)
- Acetyl Methionine Sulfoxide (CAS 3054-51-1)
Recommended Standards
- Esmolol Impurity 5 (CAS 83356-59-6)
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- 4,4'-Bis(allyloxy)-3,3',5,5'-tetramethyl-1,1'-biphenyl (CAS 97115-91-8)
- Posaconazole Impurity 133 (CAS CATO-C4X-1208133)
- Mirogabalin Impurity 85 (CAS CATO-C4X-292485)
- Procaine Impurity 27 (CAS CATO-C4X-262327)
- 4-Ethyl-5-(4-methoxyphenyl)-3-(methylthio)-1-phenyl-1H-pyrazole (CAS 871110-29-1)
- Baricitinib Impurity 120 (CAS CATO-C4X-2260120)
- Dimethyl 3-methylpentanedioate (CAS 19013-37-7)
- 1-(4-Chlorophenyl)-3-((4-fluorophenyl)sulfonyl)propan-1-one (CAS 477334-20-6)
- [4-(Dimethylamino)phenyl]methanethiol (CAS 113686-44-5)
- 1,4-Diazabicyclo[3.2.1]octane hydrochloride (CAS 2108610-85-9)
- Peptide 439 (CAS CATO-CPTD788439)
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