5-Bromo-4-(chloromethyl)-1-methyl-1H-pyrazole CAS 1879308-39-0
| CAS No. | 1879308-39-0 |
| Molecular Formula | C5H6BrClN2 |
| Molecular Weight | 209.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Bromo-4-(chloromethyl)-1-methyl-1H-pyrazole is closely related to a nitrile group, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Bromo-4-(chloromethyl)-1-methyl-1H-pyrazole (CAS 1879308-39-0), molecular formula C5H6BrClN2 and molecular weight 209.47 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Bromo-4-(chloromethyl)-1-methyl-1H-pyrazole (C5H6BrClN2) is characterized by a nitrile group, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Bromo-4-(chloromethyl)-1-methyl-1H-pyrazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H6BrClN2 |
| Molecular Weight | 209.47 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 4-bromo-5-(chloromethyl)-1-methyl-1H-pyrazole (CAS 1356543-56-0)
- 3-Bromo-5-(chloromethyl)-1-methyl-1H-pyrazole (CAS 2109428-60-4)
- 4-Bromo-1-(2-chloroethyl)-1H-pyrazole (CAS 663941-72-8)
- 4-Bromo-3-(chloromethyl)-1-methyl-1H-pyrazole (CAS 915707-66-3)
- 4-Bromo-5-chloro-1,3-dimethyl-1h-pyrazole (CAS 29939-06-8)
- 5-Bromo-3-chloro-1-ethyl-1H-pyrazole (CAS 2739830-11-4)
- 5-Bromo-4-chloro-1-ethyl-1H-pyrazole (CAS 2162236-23-7)
- 1-Bromo-2-chloro-4-fluorobenzene (CAS 110407-59-5)
Recommended Standards
- 3-(Bromomethyl)-4-chloro-1-methyl-1H-pyrazole (CAS 1256562-11-4)
- Ixazomib Impurity 33 (CAS 2905-61-5)
- 1-(3,4-dihydro-2H-quinolin-1-yl)-3-(3-methyl-1-piperidinyl)-2-propanol 1-(3,4-dihydro-2H-quinolin-1-yl)-3-(3-methylpiperidin-1-yl)propan-2-ol 89-75-8 A843300 (CAS 89-75-8)
- 3,5-Dichlorobenzoyl Chloride (CAS 2905-62-6)
- 2-[(3,4,8-trimethyl-2-oxo-2h-chromen-7-yl)oxy]acetic acid (CAS 374762-29-5)
- Benzyl (tert-butoxycarbonyl)serinate (CAS 145612-59-5)
- 4-Methyl-5-(3-{[3-(trifluoromethyl)benzyl]oxy}-2-thienyl)-4H-1,2,4-triazole-3-thiol (CAS 343376-10-3)
- Elagolix Impurity 113 (CAS CATO-C4X-2068113)
- N-ethyl-2,2-dimethyl-1,3-dioxan-5-amine (CAS 1691966-59-2)
- 1-Phenyl-4,5,6,7-tetrahydro-1h-pyrazolo[3,4-c]pyridine 2hcl (CAS 2102408-53-5)
- Ethyl 2,6-dichloro-4-fluorobenzoate (CAS 1803820-65-6)
- Carfilzomib Impurity 43 (CAS 247068-85-5)
- (9,9-Dihexyl-7-(trimethylsilyl)-9H-fluoren-2-yl)boronic acid (CAS 871468-23-4)
- Gly-Neuroendocrine Regulatory Peptide-3 (human, mouse, rat) trifluoroacetate salt (CAS 1815618-19-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com