1-(Benzyloxy)-2-chloro-3-fluorobenzene CAS 1881289-28-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1881289-28-6
Molecular FormulaC13H10ClFO
Molecular Weight236.67 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(Benzyloxy)-2-chloro-3-fluorobenzene CAS 1881289-28-6 chemical structure

Description

The occurrence of 1-(Benzyloxy)-2-chloro-3-fluorobenzene is closely related to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1-(Benzyloxy)-2-chloro-3-fluorobenzene (CAS 1881289-28-6), molecular formula C13H10ClFO and molecular weight 236.67 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 1-(Benzyloxy)-2-chloro-3-fluorobenzene is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 236.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1-(Benzyloxy)-2-chloro-3-fluorobenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H10ClFO
Molecular Weight236.67 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Cl-containing

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