3-Fluoro-5-[(piperidin-1-yl)carbonyl]phenol CAS 1881329-53-8
| CAS No. | 1881329-53-8 |
| Molecular Formula | C12H14FNO2 |
| Molecular Weight | 223.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 223.24 g/mol gives 3-Fluoro-5-[(piperidin-1-yl)carbonyl]phenol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Fluoro-5-[(piperidin-1-yl)carbonyl]phenol (CAS 1881329-53-8) is a high-purity analytical reference standard with the molecular formula C12H14FNO2 and a molecular weight of 223.24 g/mol.
The molecular framework of 3-Fluoro-5-[(piperidin-1-yl)carbonyl]phenol (C12H14FNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-Fluoro-5-[(piperidin-1-yl)carbonyl]phenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H14FNO2 |
| Molecular Weight | 223.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 1-[2-fluoro-6-(morpholin-4-yl)phenyl]ethan-1-one (CAS 1019569-01-7)
- 1-(3-Fluoro-benzyl)-pyrrolidine-2-carboxylic acid (CAS 1026092-99-8)
- (2-Fluoro-phenyl)-(4-hydroxy-piperi (CAS 1082804-68-9)
- 5-Fluoro-2-(piperidin-1-yl)benzoic acid (CAS 1096861-93-6)
- Methyl 2-fluoro-4-(pyrrolidin-2-yl)benzoate (CAS 1128075-28-4)
- 2-Fluoro-5-(dimethoxymethyl)benzonitrile (CAS 1176161-37-7)
- 4-Fluoro-N-(tetrahydro-2h-pyran-4-yl)benzamide (CAS 1183009-46-2)
- (3-Fluoro-4-hydroxypiperidin-1-yl)(phenyl)methanone (CAS 1230788-74-5)
Recommended Standards
- 4-Fluoro-3-[(piperidin-1-yl)carbonyl]phenol (CAS 1881291-18-4)
- 3’-Fluoro-4’-morpholinoacetophenone (CAS 189763-65-3)
- (4-Fluoro-2-methoxyphenyl)(pyrrolidin-1-yl)methanone (CAS 1875060-55-1)
- 5-(trifluoromethyl)-9-oxa-2-azaspiro[5.5]undecane (CAS 1909327-15-6)
- (E)-3-(5-(2-methoxy-4-nitrophenyl)furan-2-yl)acrylic acid (CAS 765926-61-2)
- 2-Hydroxy-7-methoxynaphthalene-1,4-dione (CAS 6551-27-5)
- 6-Amino-2-morpholinopyrimidine-4-carbonitrile (CAS 1353875-74-7)
- 4-Cyano-3-fluorophenyl 4-pentylbenzoate (CAS 86786-89-2)
- Olopatadine Impurity 49 (CAS CATO-C4X-171849)
- Methyl 2-(2,4-dimethylphenyl)propanoate (CAS 334865-11-1)
- Ethyl 2-bromo-4-phenylthiazole-5-carboxylate (CAS 177328-30-2)
- 4,4-Difluoro-1-[(3-fluorophenyl)methyl]cyclohexane-1-carboxylic acid (CAS 1389315-16-5)
- N-Deacetyl 10-Demethyl Colchicine (CAS 3482-37-9)
- Insulin Degludec Impurity 27 (CAS CATO-C4X-215727)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com