Olopatadine Impurity 49 CAS CATO-C4X-171849
| CAS No. | CATO-C4X-171849 |
| Molecular Formula | C22H25NO3 |
| Molecular Weight | 351.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Olopatadine Impurity 49.
Olopatadine Impurity 49 (CAS CATO-C4X-171849) is a certified pharmaceutical impurity reference standard with the molecular formula C22H25NO3 and a molecular weight of 351.44 g/mol.
Olopatadine Impurity 49 (C22H25NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Olopatadine Impurity 49 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H25NO3 |
| Molecular Weight | 351.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Olopatadine Standards
- Olopatadine Impurity 51 (CAS 113806-01-2)
- Olopatadine Impurity 69 (CAS CATO-C4X-171869)
- Olopatadine Impurity 73 (CAS CATO-C4X-171873)
- Olopatadine Impurity N1 (CAS 203188-31-2)
- Olopatadine USP Related Compound B (CAS 173174-07-7)
- Olopatadine Impurity 52 (CAS 949141-21-3)
- Olopatadine-d3 N-Oxide (CAS 1246832-94-9)
- Olopatadine Amide (CAS 872041-02-6)
Recommended Standards
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- Rosuvastatin Impurity 153 (CAS CATO-C4X-1169153)
- Tofacitinib Impurity 27 (CAS 2028267-73-2)
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- 4-Hydroxyisoquinoline-8-carboxylic acid (CAS 1824051-07-1)
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