1-Chloro-4,4-difluorocyclohex-1-ene CAS 1881331-01-6
| CAS No. | 1881331-01-6 |
| Molecular Formula | C6H7ClF2 |
| Molecular Weight | 152.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-Chloro-4,4-difluorocyclohex-1-ene is closely related to fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-Chloro-4,4-difluorocyclohex-1-ene (CAS 1881331-01-6), molecular formula C6H7ClF2 and molecular weight 152.57 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Chloro-4,4-difluorocyclohex-1-ene (C6H7ClF2) is characterized by fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Chloro-4,4-difluorocyclohex-1-ene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H7ClF2 |
| Molecular Weight | 152.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-Chloro-1H-pyrrolo[3,2-c]pyridine (CAS 1000342-65-3)
- 2-(2-Chloro-4-pyridyl)acetonitrile (CAS 1000565-45-6)
- 2-(2-Chloro-3-pyridyl)acetonitrile (CAS 101012-32-2)
- 4-Chloro-2-cyano-6-methylpyridine, 97% (CAS 104711-65-1)
- Methyl 4-chloro-3-hydroxybutanoate (CAS 10488-68-3)
- 5-Chloro-2-ethynylpyridin-3-amine (CAS 1150617-82-5)
- 2-Chloro-1H-pyrrolo[2,3-b]pyridine (CAS 1174936-85-6)
- 4-Chloro-6-azaindole (CAS 1188313-15-6)
Recommended Standards
- 4-(Chloromethyl)-2,5-oxazolidinedione-d3 (CAS 1794713-40-8)
- 3-Chloro-3-fluoro-2,4-pentanedione (CAS 135664-28-7)
- 2-(4-chloropyridin-2-yl)acetonitrile (CAS 1000515-40-1)
- 2-chloro-2-fluoro-1-methylcyclopropane-1-carboxylic acid (CAS 128230-79-5)
- 5-Chlorooxazol-2-amine (CAS 1418740-52-9)
- 3-(3-Methylpyridin-2-yl)propan-1-amine dihydrochloride (CAS 1956365-42-6)
- 2-Chloro-N-cyclohexyl-9-methyl-9H-purin-6-amine (CAS 925254-29-1)
- 7-Hydroxybenzo[d][1,3]dioxole-5-carbaldehyde (CAS 81805-98-3)
- Ethyl 4-methyl-2-(1h-pyrrol-1-yl)thiazole-5-carboxylate (CAS 263386-26-1)
- 4-((Chloromethyl)sulfonyl)thiomorpholine 1,1-dioxide (CAS 1341763-94-7)
- 3-Butoxypropane-1,2-diol (CAS 624-52-2)
- 5-Isopropylthiazol-2-amine, 97% (CAS 101080-15-3)
- (6-Chloro-2-phenylimidazo[1,2-a]pyridin-3-yl)methanol (CAS 477886-82-1)
- Semaglutide impurity 260 (CAS CATO-C4X-2226260)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com