1-Ethynyl-3,5-diiodobenzene CAS 188348-48-3
| CAS No. | 188348-48-3 |
| Molecular Formula | C8H4I2 |
| Molecular Weight | 353.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Ethynyl-3,5-diiodobenzene.
1-Ethynyl-3,5-diiodobenzene (CAS 188348-48-3) is a high-purity analytical reference standard with the molecular formula C8H4I2 and a molecular weight of 353.93 g/mol.
Based on its molecular formula C8H4I2, 1-Ethynyl-3,5-diiodobenzene contains iodine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 353.93 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4I2 |
| Molecular Weight | 353.93 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | I-containing |
Related Ethynyl Standards
- 2-[8-Ethynyl-7-fluoro-3-(methoxymethoxy)-1-naphthalenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2858674-33-4)
- 5-(8-Ethynyl-6-(pyridin-2-yl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-3-yl)oxazole (CAS 2014348-91-3)
- 4-Ethynyl-1-((4-nitrophenyl)sulfonyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one (CAS 2097770-05-1)
- 1-Ethynyl-4-((4-((4-nitrophenyl)-ethynyl)phenyl)ethynyl)benzene (CAS 377776-32-4)
- 4-Ethynyl-6-fluoro-1-tosyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one (CAS 2093115-06-9)
- 1-Ethynyl-3-methylcyclohexan-1-ol (CAS 24580-53-8)
- 4-Ethynyl-1,4-dihydro-5-methyl-1-[(4-methylphenyl)sulfonyl]-2H-3,1-benzoxazin-2-one (CAS 2236555-88-5)
- 4-Ethynyl-1,4-dihydro-8-methyl-1-[(4-methylphenyl)sulfonyl]-2H-3,1-benzoxazin-2-one (CAS 2005451-25-0)
Recommended Standards
- N-(4-(2-chlorophenyl)thiazol-2-yl)-2-thiomorpholinoacetamide (CAS 338749-94-3)
- 5-{[(2-Chlorobenzyl)thio]methyl}-4-cyclohexyl-4H-1,2,4-triazole-3-thiol (CAS 540518-43-2)
- 1-(3-Chlorophenyl)-3-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)urea (CAS 86398-88-1)
- Pitolisant impurity 11 (CAS CATO-C4X-252011)
- 4-((6-(Trifluoromethyl)pyridin-2-yl)oxy)benzenesulfonamide (CAS 1858256-85-5)
- 6-(Methoxymethyl)pyridine-2-carboxaldehyde (CAS 890904-66-2)
- (1-Methyl-3-phenyl-5-tosyl-1H-pyrazol-4-yl)methanol (CAS 318234-00-3)
- n-(4-Bromophenyl)azepane-1-carboxamide (CAS 328539-12-4)
- alpha,2-Dimethyl-4-nitrobenzyl Amine (CAS 1337030-78-0)
- tert-Butyl (6-(bromomethyl)pyridazin-3-yl)carbamate (CAS 2090236-06-7)
- Lurasidone Impurity 68 (CAS CATO-C4X-102868)
- 8-Bromo-5H-pyrido[3,2-b]indole (CAS 1236349-67-9)
- 2,2,2-Trifluoroethyl 2-(morpholin-4-ylmethyl)pyrrolidine-1-carboxylate (CAS 1306605-24-2)
- Gastric Inhibitory Polypeptide (6-30) amide (human) (CAS 1139691-72-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com