Tramadol Impurity 1 CAS 1884-42-0
| CAS No. | 1884-42-0 |
| Molecular Formula | C13H18O2 |
| Molecular Weight | 206.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Tramadol Impurity 1 (CAS 1884-42-0), molecular formula C13H18O2 and molecular weight 206.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Tramadol Impurity 1 (C13H18O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Tramadol Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H18O2 |
| Molecular Weight | 206.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Tramadol Standards
- Tramadol Impurity 10 (CAS 192384-41-1)
- Tramadol Hydrochloride EP Impurity C (CAS 905592-54-3)
- Tramadol Impurity 20 (CAS CATO-C4X-149820)
- Tramadol EP Impurity D ( and Enantiomer) (CAS 80456-81-1)
- Tramadol Hydrochloride EP Impurity E (CAS CATO-C4X-149812)
- (-)-Tramadol (CAS 123134-25-8)
- Tramadol EP Impurity A (CAS 152538-36-8)
- Tramadol Impurity 4 (CAS 2914-77-4)
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- 5-chloro-3-methyl-imidazo[4,5-b]pyridine (CAS 83472-65-5)
- 6-Chloro-8-methyl-3-phenylquinolin-2-amine (CAS 948293-48-9)
- Ethyl 4,5-dimethyl-1-oxaspiro[2.5]octane-2-carboxylate (CAS 1561284-14-7)
- 2-Amino-1-(piperidin-1-yl)ethanone (CAS 5649-08-1)
- Semaglutide impurity 36 (CAS CATO-C4X-222636)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com