Fluconazole Impurity 12 CAS 188416-33-3
| CAS No. | 188416-33-3 |
| Molecular Formula | C6H6BrClN2 |
| Molecular Weight | 221.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Fluconazole Impurity 12 (CAS 188416-33-3), a pharmacopoeial impurity reference standard (molecular formula C6H6BrClN2, MW 221.48 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C6H6BrClN2, Fluconazole Impurity 12 contains a nitrile group, chlorine/bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 221.48 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Fluconazole Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H6BrClN2 |
| Molecular Weight | 221.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Fluconazole Standards
- Fluconazole EP Impurity E (CAS 86404-63-9)
- Fluconazole Impurity 41 (CAS CATO-C4X-101941)
- Fluconazole Impurity 46 (CAS 2013304-99-7)
- Fluconazole Impurity 40 (CAS 206050-23-9)
- Fluconazole Impurity 28 (CAS CATO-C4X-101928)
- Fluconazole Impurity 29 (CAS CATO-C4X-101929)
- Fluconazole Impurity 18 (CAS 383127-79-5)
- Fluconazole EP Impurity C (CAS 514222-44-7)
Recommended Standards
- 1-Bromo-3-chloro-5-methoxybenzene (CAS 174913-12-3)
- Glumetinib Impurity 14 (CAS CATO-C4X-325914)
- 6-Bromo-5-chloro-4-methylpyridin-2-amine (CAS 2820537-11-7)
- 1-Bromo-4-chloro-2-methoxybenzene (CAS 174913-09-8)
- Baloxavir Impurity 3 (CAS 1985606-14-1)
- Lopinavir Impurity 31 (CAS CATO-C4X-168231)
- Digoxin EP Impurity B (CAS 4562-36-1)
- 2-Amino-9,9-diphenylfluorene (CAS 1268519-74-9)
- ((1,4-Phenylenebis(oxy))bis(4,1-phenylene))bis((4-fluorophenyl)methanone) (CAS 93597-87-6)
- n-(2-(Pyridin-3-yl)ethyl)thieno[3,2-d]pyrimidin-4-amine (CAS 1179669-47-6)
- 2-Amino-1-methylpyridin-4(1H)-one (CAS 1314956-46-1)
- Carbidopa Impurity 25 (CAS CATO-C4X-231025)
- N-(4-Cyclopropoxy-2-iodophenyl)methanesulfonamide (CAS 1243481-75-5)
- Semaglutide（sodium salt） (CAS CATO-C4X-222619)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com