2-(2-Chloroacetamido)-n-(4-chlorophenyl)benzamide CAS 18871-31-3

Purity 97%+In StockPharmaceutical Standards
CAS No.18871-31-3
Molecular FormulaC15H12Cl2N2O2
Molecular Weight323.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(2-Chloroacetamido)-n-(4-chlorophenyl)benzamide CAS 18871-31-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-Chloroacetamido)-n-(4-chlorophenyl)benzamide.

2-(2-Chloroacetamido)-n-(4-chlorophenyl)benzamide (CAS 18871-31-3) is a high-purity analytical reference standard with the molecular formula C15H12Cl2N2O2 and a molecular weight of 323.17 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2-(2-Chloroacetamido)-n-(4-chlorophenyl)benzamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 323.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(2-Chloroacetamido)-n-(4-chlorophenyl)benzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H12Cl2N2O2
Molecular Weight323.17 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1962
Halogen ContentCl-containing
Nitrogen Atoms2

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