1,3,4-Thiadiazole-2,5-dicarbonyl dichloride CAS 188935-32-2
| CAS No. | 188935-32-2 |
| Molecular Formula | C4Cl2N2O2S |
| Molecular Weight | 211.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, 1,3,4-Thiadiazole-2,5-dicarbonyl dichloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 211.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 1,3,4-Thiadiazole-2,5-dicarbonyl dichloride (CAS 188935-32-2), a certified reference material (molecular formula C4Cl2N2O2S, MW 211.03 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4Cl2N2O2S |
| Molecular Weight | 211.03 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Thiadiazole Standards
- 5-Benzyl-1,3,4-thiadiazole-2-thiol (CAS 29546-25-6)
- 5-Phenyl-1,3,4-thiadiazole-2-carboxylic acid (CAS 103028-60-0)
- 4-Phenyl-1,2,3-thiadiazole-5-carboxylic acid (CAS 78875-63-5)
- 4-Phenyl-1,2,5-thiadiazole-3-carboxylic acid (CAS 72234-46-9)
- 5-Phenyl-1,2,3-thiadiazole-4-carboxylic acid (CAS 58792-15-7)
- 5-Benzyl-1,2,3-thiadiazole-4-carboxylic acid (CAS 1707378-49-1)
- 4-Phenyl-1,2,3-thiadiazole-5-carbohydrazide (CAS 58756-27-7)
- 1,2,3-Thiadiazole-5-carboxylic acid, 4-(1-methylethyl)-, ethyl ester (9CI) 183302-79-6 (CAS 183302-79-6)
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