Rupatadine impurity 8 CAS CATO-C4X-10278
| CAS No. | CATO-C4X-10278 |
| Molecular Formula | C26H26ClN3O |
| Molecular Weight | 431.96 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Rupatadine impurity 8 (CAS CATO-C4X-10278), a pharmacopoeial impurity reference standard (molecular formula C26H26ClN3O, MW 431.96 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C26H26ClN3O, Rupatadine impurity 8 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 431.96 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Rupatadine impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H26ClN3O |
| Molecular Weight | 431.96 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Rupatadine Standards
- Rupatadine Impurity 16 (CAS CATO-C4X-102716)
- Rupatadine impurity 17 (CAS CATO-C4X-102717)
- Rupatadine impurity 7 (CAS 1704730-21-1)
- Rupatadine Impurity 42 (CAS CATO-C4X-102742)
- Rupatadine Impurity 38 (CAS CATO-C4X-102738)
- Rupatadine impurity 6 (CAS 156523-04-5)
- Rupatadine Impurity 43 (CAS CATO-C4X-102743)
- Rupatadine impurity 12 (CAS CATO-C4X-102712)
Recommended Standards
- 2-Acetamido-5-(chlorosulfonyl)phenyl dodecanoate (CAS 88963-77-3)
- Losartan-d9 (CAS 1030937-18-8)
- 2-((5-(2-Chlorophenyl)-4-cyclopentyl-4H-1,2,4-triazol-3-yl)thio)-N-(2-cyano-3-methylbutan-2-yl)acetamide (CAS 757216-11-8)
- Ethyl 2-((6-(((4-chlorophenyl)thio)methyl)-2-(pyridin-3-yl)pyrimidin-4-yl)thio)acetate (CAS 860609-60-5)
- Domperidone EP Impurity B (CAS 1346598-11-5)
- Tenofovir alafenamide impurity 85 (CAS 121149-98-2)
- Nebivolol Impurity 106 (CAS 99199-99-2)
- 2-(4-Fluoro-2-methylphenyl)acetic acid, 97% (CAS 407640-40-8)
- 1,4-Cyclohexadiene-1-carboxaldehyde, 4-(1-methylethyl)- 22580-90-1 CTK0J6289 (CAS 22580-90-1)
- 4-(5-Hydroxypyrimidin-2-yl)benzonitrile (CAS 150405-59-7)
- Sodium anthracene-2-sulfonate (CAS 16106-40-4)
- 2-Methyl-1,4-phenylene diacetate (CAS 717-27-1)
- 3-Methyl-2-oxo-1,2,3,4-tetrahydroquinoxaline-5-carboxylic acid (CAS 1566992-83-3)
- Semaglutide impurity 59 (CAS CATO-C4X-222659)
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