3-Methyl-2-(naphthalen-1-yl)butan-2-ol CAS 189077-65-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Methyl-2-(naphthalen-1-yl)butan-2-ol.

3-Methyl-2-(naphthalen-1-yl)butan-2-ol (CAS 189077-65-4) is a high-purity analytical reference standard with the molecular formula C15H18O and a molecular weight of 214.30 g/mol.

The molecular framework of 3-Methyl-2-(naphthalen-1-yl)butan-2-ol (C15H18O) is characterized by a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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