5-Cyclopropylthiazole-2-carboxylic acid CAS 1892415-56-3
| CAS No. | 1892415-56-3 |
| Molecular Formula | C7H7NO2S |
| Molecular Weight | 169.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Cyclopropylthiazole-2-carboxylic acid (CAS 1892415-56-3), molecular formula C7H7NO2S and molecular weight 169.20 g/mol, is a CATO reference standard with documented purity and traceability.
5-Cyclopropylthiazole-2-carboxylic acid (C7H7NO2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Cyclopropylthiazole-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7NO2S |
| Molecular Weight | 169.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Cyclopropylthiazole Standards
- 4-Cyclopropylthiazole-2-carboxylic acid (CAS 1083274-67-2)
- 2-Cyclopropylthiazole-4-carboxylic acid (CAS 478366-05-1)
- N-cyclopropylthiazole-4-carboxamide (CAS 1341512-03-5)
- 2-Cyclopropylthiazole-5-carboxamide (CAS 1849379-75-4)
- Methyl 2-cyclopropylthiazole-4-carboxylate (CAS 1286744-59-9)
- Methyl 2-cyclopropylthiazole-5-carboxylate (CAS 1286744-61-3)
- 4-Cyclopropylthiazole-2-carbohydrazide (CAS 1396762-43-8)
- Methyl 5-cyclopropylthiazole-2-carboxylate (CAS 2119699-83-9)
Recommended Standards
- 2-(3-Amino-4-fluorophenyl)propan-2-ol (CAS 1891186-05-2)
- (2-Nitrophenyl)methanethiol (CAS 38508-64-4)
- 3-Amino-4-mercaptobenzoic acid (CAS 18889-18-4)
- (3-Nitrophenyl)methanethiol (CAS 77472-39-0)
- 2-Chloro-4-fluorobenzoxazole (CAS 1163123-39-4)
- 1,4-Bis((benzyloxy)carbonyl)piperazine-2-carboxylic acid (CAS 191739-36-3)
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- 3-(5-sulfanyl-1H-1,2,3,4-tetrazol-1-yl)propanoic acid (CAS 61197-34-0)
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