2-Cyclopropylthiazole-4-carboxylic acid CAS 478366-05-1

Purity 97%+In StockPharmaceutical Standards
CAS No.478366-05-1
Molecular FormulaC7H7NO2S
Molecular Weight169.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Cyclopropylthiazole-4-carboxylic acid CAS 478366-05-1 chemical structure

Description

CATO supplies 2-Cyclopropylthiazole-4-carboxylic acid (CAS 478366-05-1), a certified reference material (molecular formula C7H7NO2S, MW 169.20 g/mol) for analytical method development and quality control.

The molecular framework of 2-Cyclopropylthiazole-4-carboxylic acid (C7H7NO2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-Cyclopropylthiazole-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC7H7NO2S
Molecular Weight169.20 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms1
Sulfur Atoms1

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