Indazole Impurity 1 CAS 1893125-36-4
| CAS No. | 1893125-36-4 |
| Molecular Formula | C8H8ClN3 |
| Molecular Weight | 181.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Indazole Impurity 1 (CAS 1893125-36-4, C8H8ClN3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C8H8ClN3, Indazole Impurity 1 contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 181.62 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Indazole Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8ClN3 |
| Molecular Weight | 181.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Indazole Standards
- 1H-Indazole-5-carbonyl chloride (CAS 1307381-63-0)
- 1H-Indazole-3-carbonyl chloride (CAS 72083-74-0)
- 1H-indazole-5-carbohydrazide (CAS 1005205-25-3)
- 1H-indazole-3-methanol, 4-methoxy- (CAS 1360929-73-2)
- 1H-indazole-4-carbothioamide (CAS 1186195-08-3)
- 1H-Indazole-5-carbothioamide (CAS 1186195-09-4)
- 2h-Indazole-7-carbothioamide (CAS 1186195-19-6)
- 1H-indazole-6-carbothioamide (CAS 1186195-46-9)
Recommended Standards
- N-(4-Chlorophenyl)acrylamide (CAS 5453-48-5)
- Copper acetate (CAS 142-71-2)
- n-(3-Chlorophenyl)prop-2-enamide (CAS 7017-16-5)
- 2-(4-chloro-1,3-thiazol-2-yl)acetic acid (CAS 1392804-23-7)
- Anagrelide Impurity 39 (CAS 1003-56-1)
- Regadenoson Impurity 64 (CAS CATO-C4X-198564)
- Flurbiprofen EP Impurity E (CAS 137045-30-8)
- Fenticonazole Impurity 8 (CAS CATO-C4X-24918)
- N1,N1-dimethyl-1-(5-methylfuran-2-yl)ethane-1,2-diamine (CAS 953749-60-5)
- tert-Butyl isothiazol-3-ylcarbamate (CAS 72592-18-8)
- 2-Morpholino-3-(trifluoromethyl)pyridine (CAS 220459-52-9)
- 2-(N,1-diphenylformamido)acetic acid (CAS 119656-49-4)
- 2-(2-Methoxynaphthalen-8-yl)acetaldehyde (CAS 176727-95-0)
- T-Peptide (CAS 2022956-62-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com