5-(difluoromethyl)thiophene-2-carboxylic acid CAS 189330-23-2
| CAS No. | 189330-23-2 |
| Molecular Formula | C6H8F2O2S |
| Molecular Weight | 182.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-(difluoromethyl)thiophene-2-carboxylic acid (CAS 189330-23-2) is a high-purity analytical reference standard with the molecular formula C6H8F2O2S and a molecular weight of 182.19 g/mol.
Based on its molecular formula C6H8F2O2S, 5-(difluoromethyl)thiophene-2-carboxylic acid contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 182.19 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H8F2O2S |
| Molecular Weight | 182.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2011 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related difluoromethyl Standards
- [2-(difluoromethyl)-4-fluoro-phenyl]hydrazine (CAS 1806667-02-6)
- 3-(difluoromethyl)thiophene-2-carboxylic acid (CAS 189330-25-4)
- 1-(difluoromethyl)-1H-indol-4-amine (CAS 1429043-06-0)
- 2-(Difluoromethyl)-3-methylpyridine-4-acetonitrile (CAS 1804443-57-9)
- 2-(Difluoromethyl)-4-methylpyridine-3-acetonitrile (CAS 1805279-54-2)
- 2-(4-(Difluoromethyl)-3-methylpyridin-2-yl)acetonitrile (CAS 1805317-89-8)
- 2-(Difluoromethyl)-5-methylpyridine-3-acetonitrile (CAS 1806069-75-9)
- 2-(Difluoromethyl)-3-methylpyridine-6-acetonitrile (CAS 1806802-78-7)
Recommended Standards
- 1-(2,2,2-Trifluoroethyl)piperidin-4-amine (CAS 187217-99-8)
- methyl 3-fluoro-2-phenylpropanoate (CAS 186700-31-2)
- Methyl 2-(2-fluorophenyl)propanoate (CAS 191351-61-8)
- 1-Methyl-6-(trifluoromethyl)piperidin-3-amine (CAS 1865110-59-3)
- 5-Chloro-8-(4-piperidinylmethoxy)quinolinehydrochloride (CAS 1219979-78-8)
- 1-Methyl-5-phenyl-1H-imidazol-2-ylamine (CAS 787586-80-5)
- N-(5-Nitro-2-(pyrrolidin-1-yl)benzylidene)aniline (CAS 61200-63-3)
- (R)-2,2'-Bis(dicyclohexylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthalene (CAS 139139-87-0)
- 3163-37-9 Z79H35Z0RU 2-Hexadecenal UNII-Z79H35Z0RU (CAS 3163-37-9)
- 4-Bromo-2-(piperidin-1-yl)pyrimidine (CAS 317830-89-0)
- N-(4-Amino-2-methylphenyl)-2-(4-chloro-3,5-dimethylphenoxy)acetamide (CAS 1315350-81-2)
- 6-(tert-Butyl)-5-cyclopropoxy-N,N-dimethylpyridin-2-amine (CAS 1243374-04-0)
- 2-((3,5-Dimethylphenyl)carbamoyl)benzoic acid (CAS 69076-57-9)
- Peptide 441 (CAS CATO-CPTD788441)
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