Ethyl 5-(difluoromethyl)thiophene-3-carboxylate CAS 189331-48-4
| CAS No. | 189331-48-4 |
| Molecular Formula | C8H8F2O2S |
| Molecular Weight | 206.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Ethyl 5-(difluoromethyl)thiophene-3-carboxylate (CAS 189331-48-4) is a high-purity analytical reference standard with the molecular formula C8H8F2O2S and a molecular weight of 206.21 g/mol.
Based on its molecular formula C8H8F2O2S, Ethyl 5-(difluoromethyl)thiophene-3-carboxylate contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 206.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Ethyl 5-(difluoromethyl)thiophene-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8F2O2S |
| Molecular Weight | 206.21 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Ethyl Standards
- Ethyl 5-(difluoromethyl)thiophene-2-carboxylate (CAS 1575820-69-7)
- 1-((Difluoromethyl)sulfonyl)-4-methylbenzene (CAS 4837-17-6)
- Difluoromethyl 3-methylphenyl sulphone (CAS 4837-16-5)
- 2-(Difluoromethyl)naphthalene-7-carboxaldehyde (CAS 1261661-02-2)
- 1-(Difluoromethyl)naphthalene-4-carboxaldehyde (CAS 1261871-64-0)
- 2-(Difluoromethyl)naphthalene-3-carboxaldehyde (CAS 1261871-66-2)
- 4-(Difluoromethyl)-2-phenylpyrimidine (CAS 1261885-09-9)
- 1-(Difluoromethyl)naphthalene-3-carboxaldehyde (CAS 1261885-69-1)
Recommended Standards
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- n1,n1-Dimethyl-n3-(4-methylpentan-2-yl)propane-1,3-diamine (CAS 1020997-84-5)
- Aklomide (CAS 3011-89-0)
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- 4-(2-Ethylpiperidin-1-yl)-2-(trifluoromethyl)benzonitrile (CAS 869643-10-7)
- 4-(Benzyl(ethyl)amino)-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid (CAS 860785-50-8)
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