4,4-Difluoro-1-(4-methoxyphenyl)butane-1,3-dione CAS 189347-40-8
| CAS No. | 189347-40-8 |
| Molecular Formula | C11H10F2O3 |
| Molecular Weight | 228.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4,4-Difluoro-1-(4-methoxyphenyl)butane-1,3-dione (C11H10F2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4,4-Difluoro-1-(4-methoxyphenyl)butane-1,3-dione (CAS 189347-40-8) is a high-purity analytical reference standard with the molecular formula C11H10F2O3 and a molecular weight of 228.19 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4,4-Difluoro-1-(4-methoxyphenyl)butane-1,3-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10F2O3 |
| Molecular Weight | 228.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 1-(3,5-Difluoro-phenyl)-2-(1,3-dioxolan-2-yl)-ethanone (CAS 1263365-73-6)
- 1-(2,5-Difluoro-phenyl)-2-(1,3-dioxolan-2-yl)-ethanone (CAS 1263365-77-0)
- 2,2-Difluoro-3-(4-methoxyphenyl)cyclopropane-1-carboxylic acid (CAS 2098003-85-9)
- 4,4-Difluoro-1-(2-methoxyphenyl)butane-1,3-dione (CAS 832739-25-0)
- 4,4-Difluoro-1-(3-methoxyphenyl)butane-1,3-dione (CAS 832740-76-8)
- (R)-2-(2,4-difluoro-5-nitrophenyl)pyrrolidine (CAS 1212904-68-1)
- (S)-2-(4,5-difluoro-2-nitrophenyl)pyrrolidine (CAS 1213356-52-5)
- (S)-2-(2,4-difluoro-5-nitrophenyl)pyrrolidine (CAS 1213403-76-9)
Recommended Standards
- (1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropyl)methanol (CAS 1890666-12-2)
- 2-(trifluoromethyl)-1,3-benzothiazole-4-carbonitrile (CAS 1909336-26-0)
- (2R,3R)-2-(3,4-difluorophenyl)tetrahydrofuran-3-carboxylic acid (CAS 1820571-83-2)
- 4-(3,4-Difluorophenyl)-2-methyl-4-oxobutanoic acid (CAS 191018-57-2)
- Methyl (2r,3s)-3-(4-aminophenyl)-3-((tert-butoxycarbonyl)amino)-2-hydroxypropanoate (CAS 1177205-50-3)
- Methyl 2-(((3-ethylisoxazol-5-yl)methyl)thio)acetate (CAS 1160246-41-2)
- 4-Amino-1-(2-fluorophenyl)pyrrolidin-2-one Hydrochloride (CAS 1177345-85-5)
- 1-Benzyl-2,6-dioxo-N-(3-(trifluoromethyl)phenyl)-1,2,3,6-tetrahydropyrimidine-4-carboxamide (CAS 338412-63-8)
- 2-[2-(hydroxymethyl)pyrrolidin-1-yl]acetic acid (CAS 155681-21-3)
- 3-Amino-4-(7-methoxynaphthalen-2-yl)butanoic acid (CAS 2227989-72-0)
- 1-Benzyl-3-phenyl-1H-pyrazole-5-carboxylic acid (CAS 948292-93-1)
- 4-Bromo-6-chlorocinnoline (CAS 1824283-74-0)
- 6-Chloro-N-cyclopentyl-2-methyl-5-(m-tolyl)pyrimidin-4-amine (CAS 917895-76-2)
- Neuropeptide EI (human, mouse, rat) (CAS 125934-45-4)
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