2,2-Difluoro-3-(4-methoxyphenyl)cyclopropane-1-carboxylic acid CAS 2098003-85-9
| CAS No. | 2098003-85-9 |
| Molecular Formula | C11H10F2O3 |
| Molecular Weight | 228.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2,2-Difluoro-3-(4-methoxyphenyl)cyclopropane-1-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2,2-Difluoro-3-(4-methoxyphenyl)cyclopropane-1-carboxylic acid (CAS 2098003-85-9) is a high-purity analytical reference standard with the molecular formula C11H10F2O3 and a molecular weight of 228.19 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 2,2-Difluoro-3-(4-methoxyphenyl)cyclopropane-1-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 228.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H10F2O3 |
| Molecular Weight | 228.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 1-(3,5-Difluoro-phenyl)-2-(1,3-dioxolan-2-yl)-ethanone (CAS 1263365-73-6)
- 1-(2,5-Difluoro-phenyl)-2-(1,3-dioxolan-2-yl)-ethanone (CAS 1263365-77-0)
- 4,4-Difluoro-1-(4-methoxyphenyl)butane-1,3-dione (CAS 189347-40-8)
- 4,4-Difluoro-1-(2-methoxyphenyl)butane-1,3-dione (CAS 832739-25-0)
- 4,4-Difluoro-1-(3-methoxyphenyl)butane-1,3-dione (CAS 832740-76-8)
- (R)-2-(2,4-difluoro-5-nitrophenyl)pyrrolidine (CAS 1212904-68-1)
- (S)-2-(4,5-difluoro-2-nitrophenyl)pyrrolidine (CAS 1213356-52-5)
- (S)-2-(2,4-difluoro-5-nitrophenyl)pyrrolidine (CAS 1213403-76-9)
Recommended Standards
- 4-(3,4-Difluorophenyl)-2-methyl-4-oxobutanoic acid (CAS 191018-57-2)
- 2-Nitrobenzene-1-sulfonyl Azide (CAS 6655-31-8)
- 2-(trifluoromethyl)-1,3-benzothiazole-4-carbonitrile (CAS 1909336-26-0)
- 3-Cyclopropoxy-4-Difluoromethoxy-Benzaldehyde (CAS 362718-98-7)
- 4-(6-Chloro-2-(trifluoromethyl)pyrimidin-4-yl)piperazine-1-carbaldehyde (CAS 1023813-57-1)
- 2-Amino-5-nitrobenzenesulfonic acid (CAS 96-75-3)
- 3-(aminomethyl)-1-methylcyclobutan-1-ol hydrochloride (CAS 2173105-60-5)
- Cyclopentanone Oxime (CAS 1192-28-5)
- trans-tert-butyl (4-fluorocyclohexyl)carbamate (CAS 923595-91-9)
- 4-Chloro-6-(2-fluorophenyl)-2-(1-methoxyethyl)pyrimidine (CAS 1708208-53-0)
- Phthalazine-5-carbonitrile (CAS 1891253-75-0)
- Felbamate USP Related Compound A (CAS 25451-53-0)
- 2-(2-Methyltetrahydrofuran-2-yl)benzo[d]thiazole (CAS 120822-01-7)
- Semaglutide impurity 45 (CAS CATO-C4X-222645)
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