2-Chloro-4-methoxy-6-methyl-5-nitropyrimidine CAS 1899-99-6
| CAS No. | 1899-99-6 |
| Molecular Formula | C6H6ClN3O3 |
| Molecular Weight | 203.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-4-methoxy-6-methyl-5-nitropyrimidine.
CATO supplies 2-Chloro-4-methoxy-6-methyl-5-nitropyrimidine (CAS 1899-99-6), a certified reference material (molecular formula C6H6ClN3O3, MW 203.58 g/mol) for analytical method development and quality control.
Structurally, 2-Chloro-4-methoxy-6-methyl-5-nitropyrimidine (C6H6ClN3O3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 203.58 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-4-methoxy-6-methyl-5-nitropyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H6ClN3O3 |
| Molecular Weight | 203.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 2-Chloro-N-(isoxazol-3-ylcarbamoyl)acetamide (CAS 112810-51-2)
- 4-chloro-2-methoxy-6-nitrophenol (CAS 118724-89-3)
- 3-Chloro-6-(2,2-difluoroethyl)pyrazine-2-carbonitrile (CAS 1257072-46-0)
- 6-Chloro-4-(difluoromethyl)-1H-pyrazolo[3,4-b]pyridine (CAS 1279829-79-6)
- 5-Chloro-4-methoxy-2-nitrophenol (CAS 14164-14-8)
- 2-Chloro-4-ethoxy-5-nitropyrimidine (CAS 1702077-93-7)
- 2-Chloro-5-(difluoromethyl)-5H-pyrrolo[3,2-d]pyrimidine (CAS 1934913-04-8)
- 4-Chloro-3-methoxy-5-nitropyridin-2-amine (CAS 1956379-48-8)
Recommended Standards
- 2-Amino-6-chloro-5-(difluoromethyl)nicotinonitrile (CAS 1806828-51-2)
- 2-Amino-6-chloro-3-(difluoromethyl)isonicotinonitrile (CAS 1806815-73-5)
- 6-Amino-5-chloro-3-(difluoromethyl)picolinonitrile (CAS 1806815-70-2)
- 2-(Chloromethyl)-5-nitro-2,3-dihydroimidazo[2,1-b]oxazole (CAS 73332-80-6)
- Naphthalene, 1,2,3,4-tetrahydro-1,1,2,4,4,7-hexamethyl- (CAS 2084-69-7)
- 5-Bromo-N,3-dimethoxy-N-methylpicolinamide (CAS 1171919-90-6)
- tert-Butyl 4-(2-amino-1-hydroxyethyl)piperidine-1-carboxylate (CAS 301221-57-8)
- 1-Propanaminium, N,N,N-trimethyl-3-[(2-methyl-1-oxo-2-propenyl)amino]-, chloride, homopolymer (CAS 68039-13-4)
- 6-Amino-2-chloro-3-methoxyphenol hydrochloride (CAS 1956322-80-7)
- Benzyl (2-(butylamino)-2-oxo-1-phenylethyl)carbamate (CAS 1393441-63-8)
- 7-Hydroxy Aminopterin 97772-99-1 N-[4-[[(2,4-Diamino-1,7-dihydro-7-oxo-6-pteridinyl)methyl]amino]benzoyl]- L-Glutamic Acid N-[4-[[(2,4-Diamino-7,8-dihydro-7-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid N-[p-[[(2,4-Diamino-7-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid (CAS 97772-99-1)
- 2-((4-Methoxybenzyl)amino)ethanol (CAS 64834-63-5)
- 2,4-Dichloro-7-methoxyquinoline (CAS 55934-22-0)
- Semaglutide impurity 39 (CAS CATO-C4X-222639)
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