2-Chloro-5-(difluoromethyl)-5H-pyrrolo[3,2-d]pyrimidine CAS 1934913-04-8
| CAS No. | 1934913-04-8 |
| Molecular Formula | C7H4ClF2N3 |
| Molecular Weight | 203.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Chloro-5-(difluoromethyl)-5H-pyrrolo[3,2-d]pyrimidine (CAS 1934913-04-8), molecular formula C7H4ClF2N3 and molecular weight 203.58 g/mol, is a CATO reference standard with documented purity and traceability.
2-Chloro-5-(difluoromethyl)-5H-pyrrolo[3,2-d]pyrimidine (C7H4ClF2N3) contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 2-Chloro-5-(difluoromethyl)-5H-pyrrolo[3,2-d]pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4ClF2N3 |
| Molecular Weight | 203.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
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- 3-(4-Isopropylphenyl)-2-methyl-1-propene (CAS 105737-89-1)
- 2-Methoxyisoindoline-1,3-dione (CAS 1914-20-1)
- 2-(Pyrrolidin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole (CAS 1595285-01-0)
- 1-(4-Chlorophenyl)-2-(phenylthio)ethan-1-one (CAS 33192-00-6)
- 1,4,5,8,9-Pentamethyl-9H-carbazole (CAS 27477-88-9)
- Tert-butyl ((3R,5R)-5-hydroxypiperidin-3-yl)carbamate (CAS 2306252-76-4)
- Des-Pro-Pro-Tirzepatide (CAS CATO-CPTD788696)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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