(1S,2S)-4,4-difluorocyclopentane-1,2-diol CAS 1903430-05-6
| CAS No. | 1903430-05-6 |
| Molecular Formula | C5H8F2O2 |
| Molecular Weight | 138.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (1S,2S)-4,4-difluorocyclopentane-1,2-diol.
CATO supplies (1S,2S)-4,4-difluorocyclopentane-1,2-diol (CAS 1903430-05-6), a certified reference material (molecular formula C5H8F2O2, MW 138.11 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, (1S,2S)-4,4-difluorocyclopentane-1,2-diol is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 138.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (1S,2S)-4,4-difluorocyclopentane-1,2-diol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H8F2O2 |
| Molecular Weight | 138.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
Recommended Standards
- methyl 4,4-difluorobutanoate (CAS 1866071-82-0)
- 2-(2,2-Difluorocyclopropoxy)ethanol (CAS 1955499-83-8)
- (1R,2R)-4,4-difluorocyclopentane-1,2-diol (CAS 1807938-95-9)
- (3,3-Difluorotetrahydrofuran-2-yl)methanol (CAS 2718966-09-5)
- Methyl 3-(5-formylfuran-2-yl)thiophene-2-carboxylate (CAS 255828-29-6)
- 2-(2-Chloro-3-methylpyridin-4-yl)acetonitrile (CAS 1227581-37-4)
- Methyl 7-bromo-5-fluorobenzofuran-2-carboxylate (CAS 1398504-34-1)
- (3aS,8aR)-2-(4-Methoxy-6-methylpyridin-2-yl)-8,8a-dihydro-3aH-indeno[1,2-d]oxazole (CAS 2757082-41-8)
- Triacetin-d5 (CAS 159510-46-0)
- 2-Amino-3-(indolizin-1-yl)propanoic acid (CAS 21640-44-8)
- 6-Methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (CAS 66521-83-3)
- 11-[[2,6-Bis[(4R)-4-ethyl-4,5-dihydro-2-oxazolyl]-4-pyridinyl]oxy]-1-undecanol (CAS 855861-95-9)
- 5-Chloro-3-methyl-2,3-dihydro-1H-inden-1-one (CAS 66248-97-3)
- Semaglutide Impurity 3 (CAS CATO-C4X-22263)
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