| CAS No. | 190605-03-9 |
| Molecular Formula | C21H16O12 |
| Molecular Weight | 460.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Rhein acyl-β-D-glucuronide (CAS 190605-03-9), molecular formula C21H16O12 and molecular weight 460.34 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Rhein acyl-β-D-glucuronide (C21H16O12) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Rhein acyl-β-D-glucuronide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C21H16O12 |
| Molecular Weight | 460.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |