5-Bromo-2,2,3,3-tetrafluoro-1,4-benzodioxane CAS 190903-76-5

Purity 97%+In StockPharmaceutical Standards
CAS No.190903-76-5
Molecular FormulaC8H3BrF4O2
Molecular Weight287.01 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Bromo-2,2,3,3-tetrafluoro-1,4-benzodioxane CAS 190903-76-5 chemical structure

Description

5-Bromo-2,2,3,3-tetrafluoro-1,4-benzodioxane (CAS 190903-76-5), molecular formula C8H3BrF4O2 and molecular weight 287.01 g/mol, is a CATO reference standard with documented purity and traceability.

5-Bromo-2,2,3,3-tetrafluoro-1,4-benzodioxane (C8H3BrF4O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H3BrF4O2
Molecular Weight287.01 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2011
Halogen ContentF/Br-containing

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Why CATO?