2,2-Difluoro-1,3-benzodioxole-5-boronic Acid CAS 190903-71-0
| CAS No. | 190903-71-0 |
| Molecular Formula | C7H5BF2O4 |
| Molecular Weight | 201.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,2-Difluoro-1,3-benzodioxole-5-boronic Acid.
CATO supplies 2,2-Difluoro-1,3-benzodioxole-5-boronic Acid (CAS 190903-71-0), a certified reference material (molecular formula C7H5BF2O4, MW 201.92 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 2,2-Difluoro-1,3-benzodioxole-5-boronic Acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 201.92 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,2-Difluoro-1,3-benzodioxole-5-boronic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5BF2O4 |
| Molecular Weight | 201.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 3,4-Difluoro-5-ethoxyphenylboronic acid (CAS 1162261-96-2)
- 3,4-Difluoro-2-ethoxyphenylboronic acid (CAS 1451391-69-7)
- 2,4-Difluoro-3-methoxy-5-methylphenylboronic acid (CAS 2096331-81-4)
- 2,6-Difluoro-3-ethoxyphenylboronic acid (CAS 849062-00-6)
- 3,5-Difluoro-4-methoxy-2-methylphenylboronic acid (CAS 2096338-65-5)
- (2,3-Difluoro-1,4-phenylene)diboronic acid (CAS 1190989-22-0)
- (2,5-Difluoro-1,4-phenylene)diboronic acid (CAS 1256358-83-4)
- 2,2-Difluoro-1,3-benzodioxole-5-carboxylic Acid (CAS 656-46-2)
Recommended Standards
- 3-Borono-2,6-difluorobenzoic acid (CAS 1451393-05-7)
- 4-Carboxy-2,5-difluorophenylboronic acid (CAS 1966890-13-0)
- (2,2-Difluorobenzo[d][1,3]dioxol-4-yl)boronic acid (CAS 126120-87-4)
- 3-(Dihydroxyboranyl)-2,5-difluorobenzoic acid (CAS 2377605-94-0)
- 2-(1h-Tetrazol-5-yl)piperidine (CAS 112626-52-5)
- 2-(1-Isopropyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)ethanol (CAS 1823321-47-6)
- (R)-3-amino-2-(benzylamino)propan-1-ol (CAS 150482-72-7)
- 2-Amino-4,5-dimethyl-1-phenethyl-1H-pyrrole-3-carbonitrile (CAS 55817-73-7)
- 2-(N-(2-fluorobenzyl)methylsulfonamido)benzoic acid (CAS 952946-42-8)
- Chromotropic Acid Disodium Salt (CAS 129-96-4)
- 1-(2-Fluorophenyl)-4-(4-(methylsulfonyl)-2-nitrophenyl)piperazine (CAS 852225-19-5)
- Diethyl 1-Methylpyrrolidine-2,5-dicarboxylate (CAS 91334-03-1)
- (S)-2-(4-Fluorophenyl)pyrrolidine (CAS 298690-90-1)
- Polyphemusin II-Derived Peptide (CAS 229030-20-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com