rac-(3R,4S)-1-benzyl-3-(3-fluorophenyl)-4-nitropyrrolidine CAS 1909288-50-1

Purity 97%+In StockPharmaceutical Standards
CAS No.1909288-50-1
Molecular FormulaC17H17FN2O2
Molecular Weight300.33 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

rac-(3R,4S)-1-benzyl-3-(3-fluorophenyl)-4-nitropyrrolidine CAS 1909288-50-1 chemical structure

Description

The occurrence of rac-(3R,4S)-1-benzyl-3-(3-fluorophenyl)-4-nitropyrrolidine is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

rac-(3R,4S)-1-benzyl-3-(3-fluorophenyl)-4-nitropyrrolidine (CAS 1909288-50-1) is a high-purity analytical reference standard with the molecular formula C17H17FN2O2 and a molecular weight of 300.33 g/mol.

The molecular framework of rac-(3R,4S)-1-benzyl-3-(3-fluorophenyl)-4-nitropyrrolidine (C17H17FN2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), rac-(3R,4S)-1-benzyl-3-(3-fluorophenyl)-4-nitropyrrolidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC17H17FN2O2
Molecular Weight300.33 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF-containing
Nitrogen Atoms2

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