trans-3-[3-(trifluoromethoxy)phenyl]cyclobutan-1-amine hydrochloride CAS 1909288-49-8
| CAS No. | 1909288-49-8 |
| Molecular Formula | C11H12F3NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of trans-3-[3-(trifluoromethoxy)phenyl]cyclobutan-1-amine hydrochloride (C11H12F3NOHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies trans-3-[3-(trifluoromethoxy)phenyl]cyclobutan-1-amine hydrochloride (CAS 1909288-49-8), a certified reference material (molecular formula C11H12F3NOHCl, MW 267.67 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), trans-3-[3-(trifluoromethoxy)phenyl]cyclobutan-1-amine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12F3NO HCl |
| Molecular Weight | 267.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related trans Standards
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- 3-(4-(Trifluoromethoxy)phenyl)propan-1-ol (CAS 1000519-40-3)
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Recommended Standards
- 6-Amino-3H-pyrazolo[3,4-d]pyrimidin-4(5H)-one (CAS 570409-64-2)
- 2-Bromo-5-(bromomethyl)-6-chloro-3-(difluoromethyl)pyridine (CAS 1805007-45-7)
- Methanone, [4-bromo-3-(2,2,2-trifluoroethoxy)phenyl]-1-pyrrolidinyl- (CAS 1443764-12-2)
- 299433-10-6 6-(Hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-1-(1-naphthalenylsulfonyl)-1H-indoledihydrochloride (CAS 299433-10-6)
- Tert-butyl (((2R,4R)-4-(trifluoromethyl)pyrrolidin-2-yl)methyl)carbamate (CAS 2306246-16-0)
- 3-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-5-yl]amino]propanoic acid (CAS 2412056-29-0)
- N1-Phenyl-N4,N4-di-m-tolylbenzene-1,4-diamine (CAS 308814-67-7)
- 3-((3-Methoxycyclohexyl)oxy)pyrrolidine (CAS 1344240-72-7)
- Methyl 2-(2-ethyl-7-oxo-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl)acetate (CAS 908498-20-4)
- Peptide Impurity 13 (CAS CATO-CPTD788813)
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