methyl 7-fluoro-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate hydrochloride CAS 1909320-14-4
| CAS No. | 1909320-14-4 |
| Molecular Formula | C10H10FNO3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
methyl 7-fluoro-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate hydrochloride (CAS 1909320-14-4), molecular formula C10H10FNO3HCl and molecular weight 247.65 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of methyl 7-fluoro-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate hydrochloride (C10H10FNO3HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), methyl 7-fluoro-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10FNO3 HCl |
| Molecular Weight | 247.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 2-Chloro-n-(2-cyanoethyl)-n-phenylpropanamide (CAS 730950-21-7)
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- 6-Bromo-N,7-dimethylpyrido[2,3-d]pyrimidin-2-amine, 97% (CAS 1454682-79-1)
- 3-Amino-N-(3-chloro-4-methylphenyl)-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (CAS 625370-14-1)
- 4'-Fluoro-2'-nitroacetanilide (CAS 448-39-5)
- 2-(1,4-Diazepan-1-yl)-N-methylacetamide dihydrochloride (CAS 2126177-11-3)
- Methyl 2-amino-3-fluoro-4-methylbenzoate (CAS 1232407-26-9)
- (E)-3-(4-(5-propylpyridin-2-yl)phenyl)acrylic acid (CAS 732953-71-8)
- 2-(Adamantan-1-yl)-N-(4-bromophenyl)acetamide (CAS 708293-02-1)
- D-Pro37-Tirzepatide (CAS CATO-CPTD788902)
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