4'-Fluoro-2'-nitroacetanilide CAS 448-39-5
| CAS No. | 448-39-5 |
| Molecular Formula | C8H7FN2O3 |
| Molecular Weight | 198.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4'-Fluoro-2'-nitroacetanilide (CAS 448-39-5), molecular formula C8H7FN2O3 and molecular weight 198.15 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4'-Fluoro-2'-nitroacetanilide (C8H7FN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 198.15 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7FN2O3 |
| Molecular Weight | 198.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 4-Fluoro-N-methyl-2-nitrobenzamide (CAS 1018983-85-1)
- 2-(5-Fluoro-2-methoxyphenyl)-2-oxoacetic acid (CAS 1094355-95-9)
- 4-Fluoro-2-trifluoromethylbenzo-6-d<SUB>1</SUB>-nitrile-<SUP>13</SUP>C,<SUP>15</SUP>N (CAS 1216879-97-8)
- N-(2-Fluoro-6-nitrophenyl)guanidine (CAS 1217015-88-7)
- 7-Fluoro-6-nitro-3,4-dihydro-2h-benzo[b][1,4]oxazine (CAS 122138-83-4)
- 3-Fluoro-n-methyl-5-nitrobenzamide (CAS 1239596-39-4)
- 3-Fluoro-2-(methoxycarbonyl)benzoic acid (CAS 1256593-37-9)
- 2-Fluoro-6-(methoxycarbonyl)benzoic acid (CAS 1256593-39-1)
Recommended Standards
- 3-Fluoro-N-methyl-4-nitrobenzamide (CAS 658700-20-0)
- 4-Fluoro-3-(methoxycarbonyl)benzoic acid (CAS 41684-09-7)
- 3-Fluoro-5-formyl-4-methoxybenzoic acid (CAS 2137718-44-4)
- 4-Fluoro-N-methyl-3-nitrobenzamide (CAS 475216-25-2)
- Gancaonin B (CAS 124596-86-7)
- (5Z)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-ol (Z)-(+/-)-5-(3-Bromopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol 156458-91-2 (CAS 156458-91-2)
- cis-2,6-dimethyloxane-4-carbaldehyde (CAS 1263775-50-3)
- 2-(Difluoromethyl)-5-fluoro-3-methylpyridine-6-sulfonamide (CAS 1805529-38-7)
- 2-(2-((6-Methoxypyridin-3-yl)carbamoyl)phenyl)acetic acid (CAS 811841-72-2)
- Ethyl 3-(2-bromo-6-chlorophenyl)propanoate (CAS 1261455-37-1)
- 3-(Chloromethyl)-5-(piperidin-1-yl)-1,2,4-oxadiazole (CAS 1393567-57-1)
- 4-[2-(2-Iodophenoxy)ethyl]piperidine hydrochloride (CAS 1220016-40-9)
- 2-Fluoro-6-methoxy-3-(trifluoromethyl)pyridine (CAS 136353-05-4)
- D-Ala35-Tirzepatide (CAS CATO-CPTD788904)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com