1-Bromo-8-(chloromethyl)naphthalene CAS 19190-48-8
| CAS No. | 19190-48-8 |
| Molecular Formula | C11H8BrCl |
| Molecular Weight | 255.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-Bromo-8-(chloromethyl)naphthalene (CAS 19190-48-8) is a high-purity analytical reference standard with the molecular formula C11H8BrCl and a molecular weight of 255.54 g/mol.
Owing to chlorine/bromine substitution, an aromatic ring system, 1-Bromo-8-(chloromethyl)naphthalene is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 255.54 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H8BrCl |
| Molecular Weight | 255.54 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl/Br-containing |
Related Bromo Standards
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Recommended Standards
- 3-(Bromomethyl)-1-chloronaphthalene (CAS 191106-25-9)
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- (3-Bromo-2-chloro-6-fluorophenyl)(methyl)sulfane (CAS 2166631-47-4)
- (3-Bromo-5-chloro-2-fluorophenyl)(methyl)sulfane (CAS 2169642-90-2)
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- Semaglutide impurity 69 (CAS CATO-C4X-222669)
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