N-(4-Fluorophenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide CAS 850567-58-7
| CAS No. | 850567-58-7 |
| Molecular Formula | C19H21BFNO3 |
| Molecular Weight | 341.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 341.18 g/mol gives N-(4-Fluorophenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(4-Fluorophenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 850567-58-7) is a high-purity analytical reference standard with the molecular formula C19H21BFNO3 and a molecular weight of 341.18 g/mol.
The molecular framework of N-(4-Fluorophenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (C19H21BFNO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(4-Fluorophenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H21BFNO3 |
| Molecular Weight | 341.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- n-(3-Fluorophenyl)-3-iodobenzamide (CAS 349118-34-9)
- N-(5-(4-Fluorophenyl)-1,3,4-oxadiazol-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide (CAS 897734-98-4)
- N-(4-fluorophenyl)-5-methyl-1-(4-nitrophenyl)-1H-1,2,4-triazole-3-carboxamide (CAS 321431-08-7)
- 1-(4-Fluorophenyl)-4-(3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one (CAS 941893-23-8)
- (4-Fluorophenyl)(4-(5-(furan-2-yl)-1,3,4-oxadiazol-2-yl)piperidin-1-yl)methanone (CAS 1172346-06-3)
- 2-(3-(4-Fluorophenyl)-6-oxopyridazin-1(6H)-yl)-N-(furan-2-ylmethyl)propanamide (CAS 1203136-03-1)
- 3-(2-Fluorophenyl)-7-(piperidin-1-yl)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione (CAS 1396857-19-4)
- 2-((4-(3-(2-Fluorophenyl)ureido)but-2-yn-1-yl)oxy)benzamide (CAS 1448054-00-9)
Recommended Standards
- N-(4-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzamide (CAS 2246760-60-9)
- N-(5-amino-2-methoxyphenyl)-2-(2,4-dichlorophenoxy)acetamide (CAS 1020054-37-8)
- N-(3-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzamide (CAS 2246676-56-0)
- Tert-butyl 4-(iodomethyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate (CAS 1087789-13-6)
- 2-(Aminomethyl)-3-chloro-4-(difluoromethyl)-5-(trifluoromethyl)pyridine (CAS 1806941-28-5)
- 2-Methyl-n-(piperidin-3-ylmethyl)propanamide (CAS 1016685-94-1)
- 1-Cyclopropyl-3-(3,4-dichlorophenyl)-1-(2-(thiophen-2-yl)ethyl)urea (CAS 1396806-68-0)
- Afatinib Impurity 91 (CAS 2512206-82-3)
- 4-(6-Amino-9H-purin-9-yl)butan-1-ol (CAS 715-68-4)
- (2-(Aminomethyl)-4-fluorophenyl)boronic acid (CAS 850689-31-5)
- 2-Ethoxy-3-methoxybenzoic acid (CAS 773869-96-8)
- 8-(chloromethyl)-6-fluoro-2-phenyl-4H-1,3-benzodioxine (CAS 730992-77-5)
- 4-Methyl-N-(2-(3-methylisoxazol-5-yl)ethyl)-2-(1H-pyrrol-1-yl)thiazole-5-carboxamide (CAS 1421472-50-5)
- Semaglutide impurity 64 (CAS CATO-C4X-222664)
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