Flibanserin Impurity 14 CAS 191977-79-4
| CAS No. | 191977-79-4 |
| Molecular Formula | C20H20Cl2N4O2 |
| Molecular Weight | 419.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Flibanserin Impurity 14 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Flibanserin Impurity 14 (CAS 191977-79-4, C20H20Cl2N4O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Flibanserin Impurity 14 (C20H20Cl2N4O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H20Cl2N4O2 |
| Molecular Weight | 419.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Flibanserin Standards
- Flibanserin N-Oxide (CAS CATO-C4X-19818)
- Flibanserin Impurity 6 (CAS CATO-C4X-19816)
- Flibanserin (CAS 167933-07-5)
- Flibanserin Impurity 19 (CAS 1642340-14-4)
- Flibanserin Impurity 17 (CAS 1971858-36-2)
- Flibanserin Impurity 11 (CAS CATO-C4X-198111)
- Flibanserin Impurity 15 (CAS 51299-16-2)
- Flibanserin Impurity 7 (CAS CATO-C4X-19817)
Recommended Standards
- Doxapram Impurity 36 (CAS CATO-C4X-197336)
- 1,8-Bis(6-chloro-9H-purin-9-yl)octane (CAS 139120-35-7)
- Doxapram Impurity 31 (CAS 1415394-56-7)
- methyl 1-(benzyloxy)-6-bromo-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylate (CAS 1638504-00-3)
- Mirabegron Impurity 109 (CAS CATO-C4X-1032109)
- Captopril EP Impurity A (Captopril disulfide) (CAS 64806-05-9)
- Diacerein EP Impurity F (CAS 13928-72-8 (racemic))
- Fluralaner Impurity 11 (CAS CATO-C4X-218011)
- 1,6-Naphthalenedicarbonitrile, 97% (CAS 46289-40-1)
- 2-(4-Methoxyphenyl)-2-oxoacetic acid (CAS 7099-91-4)
- Boc-Glu-Lys-Lys-AMC (CAS 73554-85-5)
- 2,6-Dimethylpyrimidin-4-yl 2-chloro-6-fluorobenzoate (CAS 400083-83-2)
- (3-Chloropyridin-4-yl)boronic acid hydrate (CAS 1256355-22-2)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
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