Fluticasone Impurity N11 CAS 192191-46-1
| CAS No. | 192191-46-1 |
| Molecular Formula | C21H25FO5 |
| Molecular Weight | 376.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 376.42 g/mol gives Fluticasone Impurity N11 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Fluticasone Impurity N11 (CAS 192191-46-1), a pharmacopoeial impurity reference standard (molecular formula C21H25FO5, MW 376.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution, Fluticasone Impurity N11 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 376.42 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Fluticasone Impurity N11 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H25FO5 |
| Molecular Weight | 376.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |
| Halogen Content | F-containing |
Related Fluticasone Standards
- Fluticasone Impurity 78 (CAS CATO-C4X-165078)
- Fluticasone Impurity 80 (CAS CATO-C4X-165080)
- Fluticasone Impurity 87 (CAS CATO-C4X-165087)
- Fluticasone Impurity N10 (CAS 23961-95-7)
- Fluticasone Impurity 56 (CAS CATO-C4X-165056)
- Fluticasone Impurity 86 (CAS CATO-C4X-165086)
- Fluticasone Impurity 60 (CAS CATO-C4X-165060)
- Fluticasone Impurity 65 (CAS 74131-81-0)
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- 1-Methyl-4-vinyl-1H-imidazole-5-carbaldehyde (CAS 158585-84-3)
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- 1-(2-bromoethyl)-2,3-dihydro-1H-indene (CAS 38434-35-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com