5-(2-Fluoro-5-(trifluoromethyl)phenyl)-N-(p-tolyl)thiazol-2-amine CAS 1922870-70-9

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

5-(2-Fluoro-5-(trifluoromethyl)phenyl)-N-(p-tolyl)thiazol-2-amine (CAS 1922870-70-9), molecular formula C17H12F4N2S and molecular weight 352.35 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 5-(2-Fluoro-5-(trifluoromethyl)phenyl)-N-(p-tolyl)thiazol-2-amine (C17H12F4N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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