6-Fluoro-3-[(6-fluoro-4-hydroxyquinolin-3-yl)carbonyl]quinolin-4-ol CAS 1864072-59-2
| CAS No. | 1864072-59-2 |
| Molecular Formula | C19H10F2N2O3 |
| Molecular Weight | 352.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Fluoro-3-[(6-fluoro-4-hydroxyquinolin-3-yl)carbonyl]quinolin-4-ol.
6-Fluoro-3-[(6-fluoro-4-hydroxyquinolin-3-yl)carbonyl]quinolin-4-ol (CAS 1864072-59-2) is a high-purity analytical reference standard with the molecular formula C19H10F2N2O3 and a molecular weight of 352.29 g/mol.
6-Fluoro-3-[(6-fluoro-4-hydroxyquinolin-3-yl)carbonyl]quinolin-4-ol (C19H10F2N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Fluoro-3-[(6-fluoro-4-hydroxyquinolin-3-yl)carbonyl]quinolin-4-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H10F2N2O3 |
| Molecular Weight | 352.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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- 5-(2-Fluoro-5-(trifluoromethyl)phenyl)-N-(p-tolyl)thiazol-2-amine (CAS 1922870-70-9)
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- (S)-4-(4-Fluoro-2-formylphenyl)-1-(tert-butoxy-carbonyl)piperazine-2-carboxylic acid 1787206-21-6 (CAS 1787206-21-6)
- N-(5-((4-Fluoro-2-methylphenyl)carbamoyl)-2-methylphenyl)furan-2-carboxamide (CAS 853694-04-9)
- 3-(4-Fluoro-2-nitrophenoxy)-N-(tert-pentyl)-2-thiophenecarboxamide (CAS 306977-52-6)
- [exo-3-fluoro-8-(thiophene-3-carbonyl)-8-azabicyclo[3.2.1]octan-3-yl]methyl methanesulfonate (CAS 1250831-61-8)
Recommended Standards
- Ethyl 1-cyclopropyl-6,7-difluoro-8-methyl-5-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 167888-36-0)
- (5-Bromo-2-((2-((dimethylamino)methyl)phenyl)thio)phenyl)methanol (CAS 222021-57-0)
- 7-(benzenesulfonyl)-5-bromo-7H-pyrrolo[2,3-d]pyrimidine (CAS 1289190-97-1)
- 2-Amino-4-(3,4-difluorophenyl)-5-oxo-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile (CAS 331977-28-7)
- 4-(1H-Imidazol-2-yl)benzaldehyde (CAS 1022158-42-4)
- Ethyl 2-acetoxybenzoylformate (CAS 951887-78-8)
- 5-([1,1'-biphenyl]-4-yloxy)-3-methyl-1-phenyl-1h-pyrazole-4-carbaldehyde (CAS 926190-21-8)
- N-[(2-Chlorophenyl)methyl]-6-{[(4-chlorophenyl)sulfanyl]methyl}-2-methylpyrimidin-4-amine (CAS 338960-32-0)
- 1-[(3,4-Difluorophenyl)methyl]-4-nitro-1h-pyrazole (CAS 1240568-45-9)
- 1-Isopropyl-1H-1,2,4-triazole-5-carboxamide (CAS 106535-40-4)
- (±)-Muscarine Iodide (CAS 2209-02-1)
- 2-(4-Ethylpiperazin-1-yl)-2-(2-methoxyphenyl)ethan-1-amine (CAS 904806-46-8)
- 3-chlorobicyclo[1.1.1]pentan-1-ol (CAS 2227206-14-4)
- Semaglutide impurity 194 (CAS CATO-C4X-2226194)
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